多种膳食因素对不同年龄大鼠血脂、酶活性及动脉粥样硬化的影响  

Effects of Multiple Dietary Factors on Blood Lipids,LPO,Enzyme Activity and Atherosclerosis in Hypercholestrolemic Rats of Different Ages

作　　者：张令达[1,2] 冯建高[1,2] 夏惠芬[1,2] 陈道高[1,2] 高摄渊[1,2] 袁融[1,2] 

机构地区：[1]江西医学院营养卫生教研室 [2]江西医学院组织学与胚胎学教研室

出　　处：《中国公共卫生学报》1997年第4期197-199,共3页

基　　金：国家科学基金国家科学基金

摘　　要：以大鼠作实验，观察并比较了多种膳食因素联合应用，对不同年龄大鼠血清胆固醇（ＴＣ）、甘油三酯（ＴＧ）、过氧化脂质（ＬＰＯ）含量的变化和对血清谷胱甘肽过氧化物酶（ＧＳＨＰｘ）、超氧化物歧化酶（ＳＯＤ）活力的影响，及与主动脉粥样硬化关系。结果表明：大鼠自由摄食含黄豆粉、墨鱼、海哲皮、香菇、硒、ＶＡ、ＶＥ、ＶＣ、ＶＢ６等多种膳食因素能抑制大鼠ＴＣ、ＴＧ、ＬＰＯ的升高，提高ＧＳＨＰｘ和ＳＯＤ的活性，而且这些作用在不同年龄大鼠间有差异。The effect of multiple dietary factors on total cholesterol(TC),triglyceride(TG),glutatnione perooxidase(GSH P X),and activity of superoxide dimutase(SOD),in the serum of hypercholesterolemic rats had been investigated and compared.The results showed that the intake of mixed food containing multiple dietary elements such as soybean powder,cuttlefish,jellyfish,mushroom,selenium,VA,VE,VC,VB 6,etc.could inhibit the activity of GSH P X and SOD differently in rats of different age groups.Simultaneously,it may serve for the prevention of atherosclerosis.

关 键 词：膳食因素 高脂血症 动脉粥样硬化 LPO 

分 类 号：R543.5[医药卫生—心血管疾病]