超声乳化白内障吸除术对不伴青光眼剥脱综合征患者眼压的影响  

Effects of phacoemulsification on intraocular pressure of non-glaucomatous eyes with exfoliation syndrome

作　　者：刘援[1] 张海宁[1] 曹向荣[1] 李俊英[1] 葛方东 石军[1] 白淑芬[1] 

机构地区：[1]淄博康明眼科医院,中国山东省淄博市255025

出　　处：《国际眼科杂志》2007年第6期1612-1615,共4页International Eye Science

摘　　要：目的：评价白内障超声乳化吸除术对不伴青光眼的剥脱综合征（exfoliation syndrome，XFS）患者眼压（IOP）的影响。方法：接受白内障超声乳化吸除术的不伴青光眼的剥脱综合征患者36例（38眼），不伴有剥脱综合征的白内障患者76例（76眼）。透明角膜切口白内障超声乳化吸除联合折叠人工晶状体植入，术后随访6～12mo，观察术后眼压的变化。结果：XFS组与Non-XFS组术前眼压分别为16．79±2．78mmHg，15．67±2．98mmHg（P〉0．05）。XFS组术后1d；1wk；1，6，12mo眼压分别为16．32±3．26，13．59±3．55，13．24±2．38，14．53±2．27，15．10±2．09mmHg。Non-XFS组术后1d；1wk；1，6，12mo眼压分别16．15±3．12，14．48±2．48，14．35±2．18，15．05±2．17，15．21±2．42mmHg。与手术前相比，术后1wk；1，6mo XFS组患者眼压的下降程度较非XFS组的患者大（P〈0．05）。术后12个mo，XFS组患者眼压仍较术前低，对照组患者眼压逐渐回到术前水平。结论：不伴青光眼的XFS患者超声乳化白内障吸出术后眼压较手术前明显下降，其下降程度大于非XFS患者。AIM： To evaluate the intraocular pressure （IOP） response to phacoemulsification in non-glaucomatous eyes with and without exfoliation syndrome （XFS）.METHODS： A retrospective cohort study design assigned patients to two groups： exfoliation syndrome without glaucoma （XFS） group （ n = 38）, and cataract control group （n = 76）. Inclusion criteria consisted of normal IOP, and a cataract requiring phacoemulsification. Eyes with a history of ophthalmopathy or surgery that could affect IOP were excluded. All patients received corneal incision phacoemulsification with foldable intraocular lens implantation. After the surgery patients were followed up for 6 to 12 months, IOP changes were observed. RESULTS： Postoperative IOP in the XFS group were 16.32±3.26,13.59±3.55,13.24 ±2.38,14.53 ±2.27, 15.10 ± 2.09mmHg at 1 day, 1 week, 1, 6, and 12 months respectively. The IOP in the control group were 16.15 ±3.12,14.48 ±2.48,14.35 ±2.18,15.05 ±2.17,15.21 ± 2.42mmHg respectively. Patients in the XFS group had a greater decrease in postoperative IOP compared with preoperative IOP than those in the control group at 1 week, 1 month, 6 months after the surgery （P〈0.05）. At 12 months after the surgery, patients in the XFS group still had lower IOP than preoperative IOP, while patients in the control group had recovered to preoperative IOP level. CONCLUSION： Non-glaucomatous patients with exfoliation syndrome had a postoperative IOP reduction from baseline and a significantly greater patients in the cataract control group at 1 and 6 months. Phacoemulsification reduction than week, 1 month with posterior chamber intraocular lens implantation may be effective in managing patients with exfoliation syndrome who have visually significant cataract but no elevated IOP or advanced optic nerve damage.

关 键 词：超声乳化 剥脱综合征 眼压 白内障 

分 类 号：R779.66[医药卫生—眼科]