阴道镜指导下宫颈癌前病变与幽门螺旋杆菌感染相关性及治疗的研究  

Relationship and treatment between helicobacter pylori and cervic pre-cancer

作　　者：余红[1] 韩淑英[1] 岳静玲[1] 张萍[2] 陈素兰[2] 张桂荣[2] 

机构地区：[1]华北煤炭医学院基础医学部药理教研室,河北唐山063000 [2]华北煤炭医学院附属医院,河北唐山063000

出　　处：《中国内镜杂志》2007年第12期1281-1284,共4页China Journal of Endoscopy

摘　　要：目的探讨阴道镜指导下宫颈癌前病变与幽门螺旋杆菌感染的相关性及规范治疗。方法采用快速Hp尿素酶检测法筛选宫颈癌前病变的相关病例,用阴道镜和组织病理学进行诊断证实,并采用规范的灭滴灵治疗,观察幽门螺旋杆菌阳性率的改变和临床表现的变化。结果幽门螺杆菌感染与宫颈癌前病变发展为宫颈癌有相关性;规范的灭滴灵治疗可以降低幽门螺旋杆菌感染的阳性发生率,同时,可以对宫颈癌起到病因学治疗作用。结论该项研究显示幽门螺杆菌感染可能是宫颈癌发生的原因之一;采用规范的灭滴灵治疗可以消除可能引发宫颈癌的部分原因。[Objective ] To investigate the relationship and treatment between Helicobacter pylori and cervic precancer. [Methold] Rapid biopsy urease test was used to detect H.pylori infection in different classes of cervic disease of hospital patients 2004.5-2005.5, who aged from 19 to 67 years old. Pathology of the tissue and cell applied to prove the infected cases and treating them with metronidazole reduced the positive rate and clinicl characters. [Results] In our study we recognized that helicobacter pylori was one of the causes of cervic pre-cancer. [Conclusion] The study indicates helieobaeter pylori is the causative agent of eervie cancer. The use of metronidzole can reduce cervic cancer. Further studies are needed to evaluate its role in H.pylori transmission and relapse of chronic cervic erosion leading to cervic cancer.

关 键 词：幽门螺杆菌 宫颈癌 阴道镜 灭滴灵 

分 类 号：R737.33[医药卫生—肿瘤]