慢性乙型肝炎肝胆湿热证评定量表的初步编制及考评  

Preliminary Development and Evaluation of Scale for Chronic Hepatitis B with Type of Damp-Heat in Liver and Gallbladder

作　　者：郭全[1] 陈泽奇[1] 刘小珍[1] 申定珠[1] 

机构地区：[1]中南大学湘雅医院中西医结合研究所,湖南长沙410008

出　　处：《中国中医药信息杂志》2007年第7期9-12,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：湖南省卫生厅中医药科研基金资助课题(24101)

摘　　要：目的编制慢性乙型肝炎肝胆湿热证评定量表,为该证提供有效的证候识别及疗效评定工具。方法根据心理学评定量表及WHO生活质量量表的研究方法,通过文献研究、大样本流调资料的回顾、专家讨论、条目分析及经验性筛选等方法建立量表,通过对100例慢性乙型肝炎肝胆湿热证患者和30例脾胃湿热证患者的测试,对量表的信度、效度、反应度等进行了考核。结果编制出由13个条目组成的肝胆湿热证自评量表,量表的复本信度系数为0.985,分半信度系数为0.876,克朗巴赫α系数为0.861。因子分析提取2个公因子累积方差贡献率为51.897%,量表结构与理论构想基本相符。肝胆湿热组与脾胃湿热组的量表测试结果间有显著性差异(t=2.586,P=0.011),肝胆湿热证患者治疗前后的量表评测结果间有极显著性差异(t=14.630,P<0.01)。结论慢性乙型肝炎肝胆湿热证评定量表具有较好的信度、效度、反应度和可行性,可用于该证的证候识别和疗效评价。Objective To develop a specific scale for chronic hepatitis B patients with Type of Damp-Heat in Liver and Gallbladder and offer an effective instrument for differentiating and evaluating the syndrome. Methods Adhere to the methods and theory of life quality scale of WHO and scale of psychology and according to relative researches, the scale was established through studying of the documents, reviewing the large scale investigation of clinical epidemiology of Liver syndrome, discussion of the experts in TCM, item study and experienced selection. Through the test of 100 chronic hepatitis B patients with Type of Damp-Heat in Liver and Gallbladder and 30 patients with spleen-stomach damp-heat syndrome, the reliability, validity and responsibility of the scale were evaluated. Results An 13-item Self-Rating Scale for chronic hepatitis B patients with Type of Damp-Heat in Liver and Gallbladder （DHLGS） was developed and showed good reliability and validity. The alternate form reliability coefficient of the scale was 0.985, the split-half reliability coefficient was 0.876. The Cronbach＇s Alpha coefficient was 0.861. Two common factors were extracted through exploratory principal component analysis and explaining 51.897% variance. The structure of the scale was similar to the theory construction. There was significant difference between the results of DHLGS obtained from the two syndromes [t=2.586, P=0.011）. The results of DHLGS obtained from patients with Damp-Heat in Liver and Gallbladder before and after therapy were significantly different （t=14.630, P〈0.01）. Conclusion DHLGS is reliable, valid and sensitive, and can be used to differentiate and evaluate the syndrome.

关 键 词：慢性乙型肝炎 肝胆湿热证 评定量表 信度 效度 反应度 

分 类 号：R575.1[医药卫生—消化系统]