41例嗜铬细胞瘤的诊治分析  

Clinical analysis of pheochromocytoma (Report of 41 cases)

作　　者：李志立[1] 刘凡[2] 张伟[3] 杨欣国[1] 赵连友[1] 金葵花[1] 吴学勤[1] 

机构地区：[1]第四军医大学唐都医院心内科,陕西西安710038 [2]第四军医大学唐都医院泌尿外科,陕西西安710038 [3]第四军医大学唐都医院病理科,陕西西安710038

出　　处：《中国现代医学杂志》2007年第23期2896-2898,共3页China Journal of Modern Medicine

摘　　要：目的提高嗜铬细胞瘤(PCM)的诊治水平。方法41例手术治疗的住院患者。对患者一般资料、病理、临床表现、血清生物化学及肿块病理性质等进行分析。结果有阵发性高血压者30例(73.2%),24h尿VMA浓度显著升高(126.40±39.00)μmol/24h。肿瘤大小(4.52±2.68)cm×(4.38±2.55)cm,髓质嗜铬细胞瘤占85.4%,核磁共振检出率95.1%,术后1周血压恢复正常者为30.7%。结论阵发性高血压和尿VMA浓度升高是诊断PCM最重要指标,核磁共振检查可提高疾病的诊断率。手术治疗是降低血压确实有效的治疗措施。[Objective] To study the diagnosis and treatment of pheochromycytom（PCM）. [Method] We studied 41 patients who underwent surgical excision, general status, clinical manifestations, laboratory findings and the pathology of the tumor were reviewed. [Result] 73.2% of the patients had the symptom of paroxysmal hypertension. The concentrations of the urine metanephrine was significantly higher （126.4±39.0） Pmol/24 h. The tumors were （4.52±2.68）×（4.38±2.55） cm^2. 95.1% tumors were tested by MRI scans. 30.7% patients had normal blood pressure in one week after surgical excision. [Conclusion] Paroxysmal hypertension and the urine metanephrine are important to the diagnosis of PCM. MRI scan is useful to confirm the diagnosis. Surgical treatment is an effective method to decrease the blood pressure.

关 键 词：嗜铬细胞瘤 高血压 手术 

分 类 号：R736.6[医药卫生—肿瘤]