眼红斑痤疮结膜血管损伤1773例临床研究  

Conjunctival vascular lesions in ocular rosacea

作　　者：王开文[1] 

机构地区：[1]石河子大学医学院第一附属医院眼科,新疆自治区石河子市832000

出　　处：《眼科新进展》2007年第12期926-928,共3页Recent Advances in Ophthalmology

摘　　要：目的观察眼红斑痤疮的结膜血管损伤及其出血和其他眼主要并发症的发生率。方法对眼科门诊红斑痤疮患者除用肉眼观察眼部、鼻面部相关损伤以外,主要用裂隙灯及显微镜揭示上述组织的微细血管改变。其中有9例做了结膜组织病理活检,5例做了结膜荧光血管造影。结果在2003年至2005年20477例眼科门诊患者中有1773例(0.86%)患眼红斑痤疮(均为双眼)。1773例均有结膜血管改变,其中有结膜或结膜下出血192例(10.80%),出血时就诊年龄多在41～70岁者有149例(77.60%)。1773例中出现睑缘结膜炎或睑板腺炎1406例(79.30%),其中下方角膜舌状血管翳418例(23.57%),结节性结膜炎12例(0.68%),表层巩膜炎11例(0.62%),角膜炎或角膜溃疡5例(0.28%),有1例并发虹膜炎,结膜下渗漏积液5例(0.28%)。结论眼红斑痤疮突出表现是结膜血管损害,可发生渗漏出血。下方角膜舌状血管翳或角膜炎及结节性结膜炎虽不多见,但若出现,则成为诊断眼红斑痤疮的重要依据。Objective To observe the incidence of vascular lesions and its hemorrhage of the conjunctiva and of other main ocular complications in ocular rosacea. Methods Besides gross inspecting rosacea lesions of the conjunctiva, nose and face, slit-lamp and microscope were used to detect their subtle vascular changes. Conjunetival biopsy for histopathology （ in nine cases） and fluorescein angiography （ in five cases） were performed. Results Of 20 477 ophthalmic outpatients between 2003 and 2005 years, 1 773 patients （0.86%） had ocular rosacca （all are bilateral ） and conjunctival vascular lesions; conjunctival or subconjunctival hemorrhage developed in 192 cases （10. 82% ）. Of 192 cases,the age range at presentation due to the hemorrhage was 41 - 70 years （ 149 cases, 77.60% ）. Of 1 773 cases ,blepharoconjunctivitis or meibomianitis occurred in 1 406 cases （ 79.30% ）, inferior lingulate pannus in 418 cases（23.57% ） nodular conjunctivis in 12 cases （0. 68% ）, episcleritis in 11 cases （0. 62% ） ,keratitls or corneal ulcer in 5 cases （0.28%） with 1 case accompanied by iritis, and subcojunctival effusion in 5 cases（0.28% ）. Conclusion The prominent changes in ocular rosacea are vascular lesions of the conjun ctiva with deformity and telangiectasia, and may develop effusion and hemorrhage in the involved vessels. Although the inferior lingulate pannus or keratis and nodular conjunctivitis are less conmmon, if present, they become an important basis for diagnosis of ocular rosacea.

关 键 词：眼红斑痤疮 结膜血管损伤 结膜下出血 下方舌状血管翳 

分 类 号：R771.3[医药卫生—眼科]