进展期大肠癌T分期及新辅助化疗疗效的MSCT评价  

Appraisal of T-Stage and Neoadjuvant Chemothearapy Effect of Advanced Carcinoma of Large Intestine by Multi-slice Computed Tomography

作　　者：于韬[1] 罗娅红[1] 李森[1] 邱岩[1] 

机构地区：[1]辽宁省肿瘤医院医学影像科,沈阳110042

出　　处：《中国现代医生》2007年第12S期11-13,共3页China Modern Doctor

基　　金：辽宁省科技攻关计划资助项目(00225003-13);辽宁省科技攻关计划资助项目(2005225003-17)

摘　　要：目的探讨多层螺旋CT在进展期大肠癌T分期及新辅助化疗疗效评价上的应用价值。方法选自经手术治疗的进展期大肠癌患者165例,所有病例术前均行16层螺旋CT和纤维大肠镜检查。其中,42例经新辅助化疗后再次行16层螺旋CT检查并行手术治疗。阅读CT图像后,诊断病变的T分期、新辅助化疗疗效,并与术后病理对照。结果应用MSCT判定进展期大肠癌T分期的准确率为82.4%(P<0.05);判定新辅助化疗疗效准确率为88.1%(P<0.05)。结论MSCT影像因反映了进展期大肠癌的生物学行为,而与病理所见具有一致性。MSCT在诊断进展期大肠癌的T分期、新辅助化疗疗效上具有明显的价值。Objective To investigate the application values of multi-slice spiral CT in diagnosing T-stage of advanced carcinoma of large intestine and appraising its neoadjuvant chemothearapy effect. Methods 165 patients with advanced carcinoma of colon or rectum were examined with 16-slice spiral CT and colonofibroscope before operations. In the group, 42 patients also were examined with 16-slice spiral CT again after a course of neoadjuvant chemothearapy. Then all the patients accepted operations. The CT results of judging T-stage and chemical treatment effect were compared with surgical and pathological findings. Results In diagnosing advanced carcinoma of large intestine hy multi-slice spiral CT, the accuracy of judging T-stage was 82.4%%（P 〈 0.05 ）; The accuracy of judging neoadjuvant chemotherapying effect was 88.1%（P〈 0.05 ）. Conclusion Some CT findings reflecting biological behavior of advanced carcinoma of large intestine were correlated to its pathological findings. Multi-slice spiral CT is valuable in detecting advanced carcinoma of large intestine with T-stage and chemical treatment effect and also valuable in surgical intervention and treatment planning.

关 键 词：大肠癌T分期 新辅助化疗 CT 

分 类 号：R735.34[医药卫生—肿瘤]