Stratus OCT对正常人黄斑部视网膜厚度和容积的测量  

Macular thickness and volume measurements in normal chinease using stratus optical coherence Tomography

作　　者：黄丽娜[1] 成洪波[1] 樊宁[1] 赖铭莹[1] 赵军[1] 余宝花[1] 

机构地区：[1]暨南大学第二临床医学院、深圳市眼科医院,518001

出　　处：《中国实用眼科杂志》2007年第12期1314-1318,共5页Chinese Journal of Practical Ophthalmology

摘　　要：目的应用StratusOCT测量我国正常人黄斑部视网膜的厚度和容积并分析其变异程度和与年龄、屈光度和性别的关系。方法用StratusOCT对202名202眼正常人进行黄斑厚度地形图扫描（Fast Macular Thickness Map）,分区测量黄斑部视网膜的厚度和容积。资料的统计学处理应用SPSSll.5软件。结果正常人黄斑中心小凹的视网膜最薄,平均厚度为（53±18）μm,直径1mm中心环视网膜下均厚度为（188±17）μm。直径3.45mm～2.22mm的环形区域视网膜最厚,为（275±18）μm。黄斑部颞侧视网膜比鼻侧和上方视网膜薄。直径6mm和3.45mm区域黄斑容积为（6.98±0.37）mm、（2.48±0.13）mm3。黄斑容积和直径lmm中心环视网膜厚度这两个指标的变异最小。年龄、屈光度和性别对黄斑中心小凹视网膜厚度的影响没有统计学意义。黄斑容积与中心小凹视网膜厚度有正的直线相关性,与年龄有负的直线相关性。屈光度和性别对黄斑容积的影响没有统计学意义。结论StratusOCT测量我国正常人黄斑部视网膜的厚度和容积,分区测量值为黄斑疾病的诊治提供了客观、定量的指标。Objective To provide the normative data of macular thickness and volume in normal chinease using Stratus Optical Coherence Tomography （Stratus OCT）. Analyze the variation of parameters of thickness and volume, investigate the relationships between them and age, refraction and gender. Methods 202 eyes of 202 normal subjects had undergone with the scan protocol （Fast Macular Thickness Map） of Stratus OCT. The thickness of neurosenory retina in nine regions and the volume of macula were measured. The data was analyzed using SPSS 11.5 commercial statistical software. Results Central foveal thickness and foveal thickness （mean thickness in the central 1000-μm diameter area） were 153 ± 18 and 188 ± 1711m, respectively. Macular thickness measurements were thinnest at the center of the fovea, thicknest within the ring area of 3.45 mm ～ 2.22mm diameter of the center, which was 275 ± 18111m. The temporal quadrants of macula was thinner than the nasal and superior quadrants. Macular volume with 6mm and 3.45mm diameter of the center were 6.98 ± 0.37 and 2.48 ± 0.13mm3, respectively. The variations of macular volume and foveal thickness were smallest. Age, refraction and gender had no effect on central foveal thickness. There were significant positive linear correlation between macular volume and central foveal thickness, and negative linear correlation between macular volume and age. Refraction and gender had no effect on macular volume.Conclusions We provide the normative data of macular thickness and volume in normal chinease using Stratus OCT. The measurements in different regions of macula offer a subjective and quantitative method to diagnose macular diseases.

关 键 词：光学相干断层扫描 视网膜厚度 黄斑 

分 类 号：R774[医药卫生—眼科]