细胞微系统技术及其应用  

Cell Microsystem Technology and Its Application

作　　者：邵建波[1] 金庆辉[1] 赵建龙[1] 

机构地区：[1]中国科学院上海微系统与信息技术研究所

出　　处：《细胞生物学杂志》2007年第6期859-863,共5页Chinese Journal of Cell Biology

基　　金：上海市科委基金(No.051111019;No.0552nm015;No.0652nm016;No.06JC14081);上海AM基金(No.0510);国家重点基础研究发展规划(973计划)(No.2005CB724305)资助项目~~

摘　　要：细胞微系统技术研究是目前细胞生物学、微系统科学及药物筛选等学科交叉领域的一个研究热点,其综合利用了微系统平台技术,将细胞的培养、观测和分析在微系统平台上完成,丰富了细胞研究方法,为细胞研究提供了一个全新的研究平台。现对目前细胞微系统研究中几种典型的方法,如立体微结构模型、软光刻、微流体、芯片毛细管电泳、微电极等进行综述,并阐述其在细胞生物学、生命科学等领域相关研究中的应用。Recently cell microsystem technology has now been a focus in cell biology research. Cell microsystem, based on micro-electromechanical system （MEMS） technology combined with cell biology, performs cell culturing, monitoring and analysis totally on a microsystem chip. It is a novel platform for cell biology research and has achieved amazing progress in recently several years. Maybe it will be the next revolution tools for biological discovery. In this paper, we reviewed the typical methods of cell microsystem, including 3-dimensional microstructure, soft lithography, microfluidics, chip-based capillary electrophoresis, microelectrode array, also the applications in cell biological and life science research had been introduced.

关 键 词：细胞微系统 立体微结构模型 软光刻 微流体 芯片毛细管电泳 

分 类 号：Q2-3[生物学—细胞生物学]