纳米羟磷灰石对玻璃离子黏固剂的性能影响  

Effect of nano-hydroxyapatite to glass ionomer cement

作　　者：穆亚冰[1] 臧光祥[2] 孙宏晨[2] 王成坤[1] 

机构地区：[1]吉林大学口腔医院牙体牙髓病科,吉林长春130041 [2]吉林大学口腔医院病理科,吉林长春130041

出　　处：《华西口腔医学杂志》2007年第6期544-547,共4页West China Journal of Stomatology

摘　　要：目的探讨添加纳米羟磷灰石(nano-HAP)的玻璃离子黏固剂(GIC)的力学性能、充填后的材料-牙本质界面渗漏状况和矿化性能。方法将nano-HAP按8%的质量分数比均匀混入GIC粉末形成复合材料(实验组材料),单纯GIC为对照组材料。采用两种材料分别制备20个柱状样本,测定其三点弯曲强度和压缩强度。选用120颗完整的离体牙,在颊面制备Ⅴ类洞,分别采用两种材料充填后放入质量分数1%若丹明-B-异硫氰酸盐溶液中染色24 h,在激光共聚焦显微镜下观察充填界面的渗漏现象。在健康犬磨牙上制备Ⅴ类洞,分别用两种材料充填,8周后拔除充填牙,在偏振光显微镜下观察材料内部和充填界面的矿化情况。结果添加nano-HAP的GIC复合材料的三点弯曲强度、压缩强度与单纯GIC相比有所提高(P<0.001,P<0.05);添加nano-HAP的GIC复合材料和单纯GIC充填离体牙标本后均出现纳渗漏和微渗漏,但前者出现微渗漏概率较后者低(P=0.004);复合材料充填界面有新形成的羟磷灰石晶体,并沉积形成矿化带,单纯GIC充填界面没有羟磷灰石晶体形成。结论添加nano-HAP的GIC充填牙齿后能形成较紧密的材料-牙本质界面,并有矿化潜能,可作为窝洞衬里或预防性充填材料应用。Objective To investigate the mechanical character,microleakage and mineralizing potential of nano-hydroxyapatite（nano-HAP）-added glass ionomer cement（GIC）.Methods 8% nano-HAP were incorporated into GIC as composite,and pure GIC as control.Both types of material were used to make 20 cylinders respectively in order to detect three-point flexural strength and compressive strength.Class Ⅴ cavities were prepared in 120 molars ex-tracted for orthodontic treatment,then were filled by two kinds of material.The microleakage at the composite-den-tine interface was observed with confocal laser scanning microscope（CLSM） after stained with 1% rhodamin-B-isoth-iocyanate for 24 hours.Class Ⅴ cavities were prepared in the molars of 4 healthy dogs,filled with composite,and the same molars in the other side were filled with GIC as control.The teeth were extracted to observe the mineral-izing property with polarimetric microscope in 8 weeks after filling.Results Three-point flexural strength and com-pressive of nano-HAP-added GIC were increased compared with pure GIC（P〈0.001,P〈0.05）.The nanoleakages and microleakages appeared at the material-dentine interface in the two groups,but there were more microleakages in control group than in experiment group（P=0.004）.New crystals of hydroxyapatite were formed into a new mineralizing zone at the interface of tooth and nano-HAP-added GIC,while there was no hydroxyapatite crystals formed at the interface of tooth and pure GIC.Conclusion 8% nano-HAP-added GIC can tightly fill tooth and have mineralizing potential,and can be used as liner or filling material for prevention.

关 键 词：玻璃离子黏固剂 纳米羟磷灰石 矿化 微渗漏 

分 类 号：R783[医药卫生—口腔医学]