乳腺癌保留乳房手术切缘阳性的临床病理学因素分析  

Correlative clinicopathologic factors of positive margin in breast conservation

作　　者：冯立民[1] 朱世光[1] 孙宪春[1] 乔广东[1] 李刚[1] 吉田和弘[2] 

机构地区：[1]山东省烟台毓璜顶医院肿瘤外科,山东烟台264000 [2]日本广岛大学原医研肿瘤外科

出　　处：《中国现代普通外科进展》2007年第6期479-481,共3页Chinese Journal of Current Advances in General Surgery

摘　　要：目的:分析保留乳房手术切缘阳性与相关临床病理学的关系,探讨保留乳房手术后复发的危险因素。方法:305例乳腺癌患者行保留乳房手术,对术中快速病理以及术后病理切缘阳性的病例进行分析,总结切缘状况与组织类型、广泛导管内成分(extensive intraductal component,EIC)、区域淋巴结转移、肿瘤大小及年龄的关系。结果:保留乳房手术切缘阳性与患者年龄(≤35岁)、EIC和浸润性小叶癌有关(P<0.05);与肿瘤大小和淋巴结转移状况无关。结论:乳腺癌行保留乳房手术时,术中应详细检查切缘状况,对年轻者、EIC、浸润性小叶癌需要慎重的选择保留乳房手术及设定切除范围。Objective： To explore the correlative clinicopathologic factrors of positive margin in breast conservation. Methods： From January 1998 to December 2003, 305 cases of breast cancer at stage Ⅰ and Ⅱ were treated by conservative operation, the relationships between Clinicopathologic characteristics and margin status were analyzed. Results： Positive margin was related with younger age （≤35）, extensive intradutal component （EIC） and invasive Iobular carcinoma（P〈0.05）. Conclusion： The margins should be examined carefully during breast conservative surgery so as to achieve negative margin.

关 键 词：乳腺肿瘤 保留乳房手术 病理学 临床 

分 类 号：R737.9[医药卫生—肿瘤]