癌症患者生命质量测定量表体系之大肠癌量表QLICP-CR的研制  

Development of the System of Quality of Life Instruments for Cancer Patients:Colorectal Cancer (QLICP-CR)

作　　者：杨铮[1] 卢玉波[2] 万崇华[1] 寸英丽[2] 李云峰[2] 许传志[1] 张晓磬[1] 

机构地区：[1]昆明医学院公共卫生学院,云南昆明650031 [2]云南省肿瘤医院,云南昆明650031

出　　处：《癌症》2008年第1期96-100,共5页Chinese Journal of Cancer

基　　金：云南省自然科学基金(No.99C0016G)~~

摘　　要：背景与目的:癌症患者生命质量测定量表体系(quality of life instrumentsfor cancer patients,QLICP)共性模块的研制已有报道,本研究在此基础上将研制大肠癌患者生命质量测定量表(QLICP-colorectal cancer,QLICP-CR)。方法:采用量表开发的程序化决策方式研制适合中国文化背景下使用的QLICP-CR,并通过110例大肠癌患者的生存质量测定对量表进行评价。采用统计描述、相关分析、配对t检验和聚类分析等进行统计学处理。结果:总量表及各个领域的重测相关系数均在0.78以上;各领域内部一致性信度的α值除社会功能及共性症状和副作用领域分别为0.66、0.63外,其余均在0.85以上;各条目与其领域的相关均大于与其它领域的相关,相关系数r值大多都在0.6以上;总量表、共性模块、特异模块、心理功能及共性症状和副作用领域得分均显示治疗前后差异有统计学意义。结论:QLICP-CR具有较好的信度、效度及反应度,可作为我国大肠癌患者生命质量的测评工具。BACKGROUND ＆ OBJECTIVE： Based on the development of the general module of the system of quality of life instruments for cancer patients （QLICP-GM）, this study was to develop and evaluate a quality of life scale for patients with colorectal cancer （QLICP-CR）. METHODS： A quality of life scale for colorectal cancer patients that associated with Chinese cultural background was developed. The data from 110 patients with colorectal cancer were analyzed using statistical description, Pearson Correlation, Cluster analysis, and paired t-student test to assess the instrument. RESULTS： The test-retest reliability for the scale and 5 domains were all above 0.78. Internal consistency cc for each domain was higher than 0.85 except for the social domain （0.66） and the symptom and side effect domain （0.63）. Most of the correlation coefficients between each item and its domains were above 0.6. The differences in the scores of overall scale, general module, special domain, psychological domain, and symptom and side effect domain between pre-treatment and post-treatment were significant. CONCLUSION. The QLICP-CR is reasonably valid, reliable, and responsible, and can be used to assess quality of life for the patients with colorectal cancer.

关 键 词：大肠肿瘤 生命质量 量表 

分 类 号：R735.34[医药卫生—肿瘤]