婴幼儿供体角膜及人工角膜在眼前并眼后段病变中的应用  

Application of Infant Donor Cornea and Temporary Keratoprosthesis for Ocular Disease of Anterior and Posterior Segment

作　　者：叶波[1] 周文天[1] 吴蓉[1] 

机构地区：[1]南昌大学第二附属医院眼科,南昌330006

出　　处：《实用临床医学（江西）》2007年第12期93-95,共3页Practical Clinical Medicine

摘　　要：目的：评价应用临时人工角膜及婴幼儿供体角膜进行穿透性角膜移植联合眼后节手术的安全性及治疗效果。方法：对复杂性眼球穿通伤所致角膜混浊同时伴有玻璃体视网膜病变8例患者8眼，施行临时人工角膜下的经睫状体平坦部的闭合式玻璃体切除、球内异物取出、视网膜复位、硅油充填、穿透性角膜移植等联合手术。结果：术后随访3月～2年，6眼视力较术前提高，其中2眼矫正视力〉0．1，4眼矫正视力0．02～0．1，2眼视力无提高。角膜移植片7眼透明，1眼角膜产生排斥反应。视网膜脱离6眼中，4眼复位，2眼再次发生视网膜脱离。结论：应用临时人工角膜及婴幼儿供体角膜进行玻璃体手术联合穿透性角膜移植术是治疗严重眼前后节受伤患者的一种有效手术方法。Objective：To evaluate the efficacy and safety of penetrating keratoplasty and posterior segments with temporary keratoprosthesis and infant donor cornea used in combined operations. Methods：With temporary keratoprosthesis a combined operation including pars plana vitrectomy, extraction of intraocular foreign body, retinal reattachment, silicone oil injection and penetrating keratoplasty was performed on 8 eyes of 8 patients with complicated perforating wound of eyeball and vitreoretinopathy. Results： Each case was followed-up for 3 - 24 months, the visual acuity was increased in 6 eyes, corrected visual acuity was 0.1 or better in 2 eyes, corrected visual acui- ty was among 0.02-0.1 in 4 eyes and was not increased in 2 eyes visual acuity. The grafts of 7 eyes remained transparent, cornea rejection （1 eye）. In 6 eyes retinal detachment,4 eyes were retinal reattachment, retinal detachment recurred in 2 eyes. Conclusions：Temporary keratoprosthesis and infant donor cornea used in the combined surgeries of vitrectomy and penetrating keratoplasty is an effective method for treatment of severe anterior and posterior ocular segments injuries.

关 键 词：临时人工角膜 婴幼儿角膜供体 穿透性角膜移植术 玻璃体手术 

分 类 号：R772.2[医药卫生—眼科]