精神分裂症患者治疗前后一氧化氮血清浓度研究  

A Study of Serum Nitric Oxide Level in Schizophrenia Patients

作　　者：王新达 张文跃[1] 陶建荣[1] 黄宏[2] 宣春明 徐慧芊 韩晓东[1] 

机构地区：[1]江苏省太仓市第三人民医院,江苏太仓215400 [2]苏州大学附属第二医院核医学科,江苏苏州215004

出　　处：《中国血液流变学杂志》2007年第4期561-562,共2页Chinese Journal of Hemorheology

摘　　要：目的了解精神分裂症患者病情变化与一氧化氮(NO)血清浓度之间的关系。方法对36例精神分裂症患者治疗前及治疗4周后NO血清浓度进行检测,采用PANSS量表进行疗效评定,以18例正常体检为对照。结果精神分裂症患者的NO血清浓度高于正常对照组,NO血清浓度与PANSS评分之间未见相关。结论精神分理解症患者存在较高的NO血清浓度,但它并不直接反映精神分裂症患者病情的轻重。Objective To understand the serum nitric oxide level in schizophrenia patients.Method The serum nitric, oxide level of 36 schizophrenia patients were detected and their paychopathologic symptoms were assessed by Positive and Negative Syndrome Scale（PANSS）.Results The serum nitric oxide level of patients were higher then those of normal controls.The serum nitric oxide level was not correlated with PANSS.Conelusion There higher serum nitric oxide level in schizophrenia patients,hut serum nitric oxide is not directly stand for schizophrenia symptom.

关 键 词：精神分裂症 一氧化氮血清浓度 

分 类 号：R749.3[医药卫生—神经病学与精神病学]