CLINICAL RESEARCH OF IMPACTS ON PLASMA ENDOTHELIN AND INTELLIGENCE IN MULTI-INFARCT DEMATIA TREATED WITH CLUSTER PRICKING ON HEAD POINTS  

头穴丛刺对多梗死性痴呆患者血浆内皮素及智能的影响(英文)

作　　者：王利春[1] 王志勇[1] 陈艳艳[1] 刘振江[1] 李宝栋[1] 杨京花[1] 程为平[2] 

机构地区：[1]沧州中西医结合医院神经内科 [2]黑龙江中医药大学附属第一医院神经二科

出　　处：《World Journal of Acupuncture-Moxibustion》2007年第4期16-21,共6页世界针灸杂志（英文版）

摘　　要：Objective To probe into the impacts on the therapeutic effects and endothelin （ET） in multi-infarct dementia （MID） treated with cluster pricking on head points.Methods 60 cases of MID were randomized into acupuncture group and western medicine group,treated with cluster pricking on head points and huperzien A tablet respectively.Plasma ET lever,HDS,ADL and CNFDS （clinical neurological functional defect scoring） were determined before treatment,and the statistical analysis showed that there were no significant difference （P〉0.05）.Results In 8-week treatment,ET level in both groups were decreased,but it was decreased much more obviously in acupuncture group,indicating significant difference in the statistical comparison （P〈0.05）.The scores of HDS and ADL were all up in acupuncture and western medicine groups,but the significant statistical difference was obtained in the comparison between acupuncture group and western medicine group （P〈0.05）.In acupuncture group,the result of CNFDS was much down comparing with that before the treatment,indicating significant difference （P〈0.05）;but in western medicine group,there was no significant difference in CNFDS before and after treatment （P〉0.05）,suggesting that acupuncture reduces CNFDS of MID patient,neither for western medicine.Conclusion Cluster pricking on head points improves the intelligence of MID patient,reduces ET level and grades up HDS and ADL,moreover,it reduces CNFDS of MID patients and releases the symptoms.目的:探讨头穴丛刺治疗多梗死性痴呆的疗效及对患者血浆内皮素的影响。方法:选取60名多梗死性痴呆(MID)患者随机分为针刺组和西药组,分别采用头穴丛刺疗法和哈伯因片治疗。治疗前后测定血浆内皮素含量及HDS、ADL及神经功能缺损评分,经统计学分析,P>0.05,两组间无显著差异。结果:经8周治疗后,两组内皮素含量均有所降低,以针刺组降低更明显,两组比较P<0.05,差异有统计学意义;针刺组与西药组HDS、ADL评分均有所提高,且与西药组比较P<0.05,差异有统计学意义;针刺组神经功能缺损评分治疗后较治疗前有大幅度降低,差异有显著性意义,P<0.05,但西药组治疗前后比较,差异无统计学意义,P>0.05,提示针刺可降低MID患者的神经功能缺损评分,而西药组不能。结论:头穴丛刺疗法可改善MID患者的智能,降低患者血浆内皮素水平,提高HDS、ADL评分,并且可降低MID患者的神经功能缺损评分,改善症状。

关 键 词：Cluster pricking/puncturing Multi-infarct dementia ENDOTHELIN Clinical research 

分 类 号：R246.6[医药卫生—针灸推拿学]