ENDOTHELIN

作品数:210被引量:416H指数:11
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Corrigendum: Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism
《Neural Regeneration Research》2025年第2期401-401,共1页
In the article titled“Astrocytic endothelin-1 overexpression impairs learning and memory ability in ischemic stroke via altered hippocampal neurogenesis and lipid metabolism,”published on pages 650-656,Issue 3,Volum...
关键词:METABOLISM ENDOTHELIN 
Cocrystal pleomorphism-inspired drug nanoassembly for pulmonary-endothelium targeting and pulmonary hypertension treatment
《Acta Pharmaceutica Sinica B》2025年第1期557-570,共14页Makhloufi Zoulikha Jiahui Zou Pei Yang Jun Wu Wei Wu Kun Hao Wei He 
supported by the National Natural Science Foundation of China(Nos.82073782 and 82241002);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(21KJA320003);the Scientific Research Project of Jiangsu Commission of Health(LKZ2023001,China);the Clinical Competence Improvement Project of Jiangsu Province Hospital(JSPH-MB-2022-13,China).
Endothelial dysfunction is one of the early triggers of vascular remodeling during pulmonary hypertension(PH)with complex predisposing mechanisms,mainly via an unbalanced generation of vasoactive factors,increased exp...
关键词:Pulmonary hypertension Inflammation Endothelial dysfunction ENDOTHELIN COCRYSTALS Nanorods BOSENTAN ANDROGRAPHOLIDE 
Effects of Dezocine and Propofol Combination on Plasma 5-HT and ET Levels in Stroke Patients Undergoing Thrombolysis
《Journal of Clinical and Nursing Research》2024年第9期234-239,共6页Fangfang Lv Xiuhong Wang Weibo Wang 
Objective: To investigate the effect of dezocine combined with propofol on brain metabolism in patients undergoing cerebral thrombosis thrombolysis. Methods: A total of 86 stroke patients admitted between July 2022 an...
关键词:DEZOCINE PROPOFOL 5-HYDROXYTRYPTAMINE ENDOTHELIN Cerebral apoplexy 
Effects of PEAR1 gene polymorphism on big endothelin-1 levels in Chinese patients with acute myocardial infarction after percutaneous coronary intervention
《World Journal of Emergency Medicine》2024年第3期229-231,共3页Yi Yao Na Xu Xiaofang Tang Ce Zhang Sida Jia Jingjing Xu Ying Song Xueyan Zhao Runlin Gao Jinqing Yuan 
National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences(NCRC2020013);CAMS Innovation Fund for Medical Sciences(2020-I2M-C&T-B-049)。
Acute myocardial infarction (AMI) has been associated with poor prognosis,even after revascularization with percutaneous coronary intervention (PCI),likely due to coronary endothelial cell dysfunction and injury.^([1,...
关键词:CORONARY PERCUTANEOUS ENDOTHELIN 
Regulatory mechanisms of retinal ganglion cell death in normal tension glaucoma and potential therapies被引量:2
《Neural Regeneration Research》2023年第1期87-93,共7页Wen-Cui Shen Bing-Qing Huang Jin Yang 
supported in part by the Technology Foundation of Tianjin Eye Hospital of China, No. YKQN1911 (to WCS);Tianjin Health Science and Technology Project, No. TJWJ2021QN071 (to WCS);Translational Medicine Research Project of State Key Laboratory of Experimental Hematology of China, No. Z21-11 (to BQH)
Normal tension glaucoma(NTG)is a multifactorial optic neuropathy characterized by normal intraocular pressure,progressive retinal ganglion cell(RGC)death,and glaucomatous visual field loss.Recent studies have describe...
关键词:AUTOPHAGY endothelin 1 glutamate neurotoxicity inhibitor nerve regeneration NEUROINFLAMMATION normal tension glaucoma oxidative stress retinal ganglion cell VASOCONSTRICTION 
Endothelins and liver cirrhosis
《Portal Hypertension & Cirrhosis》2022年第1期66-72,共7页NecatiÖrmeci 
Endothelins are a family of 21‐amino acid oligopeptides,called endothelin‐1(ET‐1),endothelin‐2(ET‐2),and endothelin 3(ET‐3).Endothelins act on hepatocytes,liver endothelial cells,and Kupffer cells in a paracrine...
关键词:CIRRHOSIS ENDOTHELIN portal hypertension 
The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice被引量:7
《Acta Pharmacologica Sinica》2021年第9期1437-1448,共12页Zhi-chao Dong Ming-ming Wu Yun-long Zhang Qiu-shi Wang Chen Liang Xiao Yan Lei-xin Zou Chen Chen Xiao Han Bo Zhang Zhi-ren Zhang 
the National Natural Science Foundation of China(Grants 81870370,81930009,and 91639202 to ZRZ);the 2017-2018 Annual Special Fund for Scientific Research and Transformation of Heilongjiang Academy of Medical Sciences(CR201810);the Nn10 Program of Harbin Medical University Cancer Hospital.
Aflibercept,as a soluble decoy vascular endothelial growth factor receptor,Which has been used as a first-line monotherapy for cancers.Aflibercept often causes cardiovascular toxicities including hypertension,but the ...
关键词:AFLIBERCEPT HYPERTENSION endothelial dysfunction superoxide production endothelin 1 cationic amino acid transporter-1 L-ARGININE cultured endothelial cells 
Is There a Relationship between Endotheline-1, Vascular Cell Adhesion Molecule-1 and the Arterial Hypotension Observed during Spinal Anesthesia?
《Journal of Biosciences and Medicines》2021年第1期64-85,共22页J. F. Nnang Essone K. Nzé Pascal G. Edjo Nkhilli N. Ekegue Diaw Mor C. P. Akagha Kondé P. Nzoghe Nguéma E. Anyunzok E. R. Obame C. Allognon B. Nguéma Asseko F. Ovono Abessolo E. Ngou Milama 
Introduction: The involvement of the endothelial dysfunction (ED) in arterial hypotension (AHPT) post of spinal anesthesia (SA) has not been established. Objective: To determine if th...
关键词:ENDOTHELIN-1 VCAM-1 HYPOTENSION ENDOTHELIAL Dysfunction Spinal ANESTHESIA 
The anti-hypertensive effect of time acupuncture on the patients with primary hypertension被引量:1
《World Journal of Acupuncture-Moxibustion》2020年第4期272-276,共5页Yan-jun WANG Xin ZHAO Xiang-dong LAN Shui-qing XU Li-hua ZHANG 
supported by National key R&D Program:No.2018YFC1707803;Subject of Hebei Provincial Department of Finance:No.361025;Project of Hebei Provincial Administration of Traditional Chinese Medicine:No.2017054。
Objective:To observe the anti-hypertensive effect of time acupuncture on primary hypertension so as to provide the therapeutic regimen for the treatment of primary hypertension.Methods:A total of 120 patients with pri...
关键词:ACUPUNCTURE Primary hypertension Anti-hypertensive effect Acupuncture combines with medication Endothelin(ET) Nitrious oxide(NO) 
Effect of Zataria multiflora Extract on Total and Differential White Blood Cell Count and Endothelin Level in Blood of Ovalbumin Sensitized Guinea Pigs
《Chinese Journal of Integrative Medicine》2020年第8期604-608,共5页Mohammad Hossein Boskabady Sediqeh Jalali 
Supported by Research Department of Mashhad University of Medical Sciences(No.89431)。
Objective:To investigate the effect of hydro-ethanolic extract of Zataria multiflora(Z.multiflora)on endothelin level,total and differential white blood cells(WBC)count of sensitized guinea pigs.Methods:Five groups of...
关键词:Zataria multiflora ASTHMA endothelin level white blood cell SENSITIZATION 
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