云南高校图书馆联盟文献共享服务平台- BOSENTAN

BOSENTAN: 作品数：24被引量：36H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：巩守平吕健王文涛权瑜宋千更多>>; 相关机构：西安交通大学医学院第二附属医院西安交通大学北京协和医学院马鞍山市人民医院更多>>; 相关期刊：《华西药学杂志》《Open Journal of Pediatrics》《南京医科大学学报（自然科学版）》《药学进展》更多>>; 相关基金：国家自然科学基金更多>>

Cocrystal pleomorphism-inspired drug nanoassembly for pulmonary-endothelium targeting and pulmonary hypertension treatment: 《Acta Pharmaceutica Sinica B》2025年第1期557-570,共14页Makhloufi Zoulikha Jiahui Zou Pei Yang Jun Wu Wei Wu Kun Hao Wei He; supported by the National Natural Science Foundation of China(Nos.82073782 and 82241002);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(21KJA320003);the Scientific Research Project of Jiangsu Commission of Health(LKZ2023001,China);the Clinical Competence Improvement Project of Jiangsu Province Hospital(JSPH-MB-2022-13,China).; Endothelial dysfunction is one of the early triggers of vascular remodeling during pulmonary hypertension(PH)with complex predisposing mechanisms,mainly via an unbalanced generation of vasoactive factors,increased exp...; 关键词：Pulmonary hypertension Inflammation Endothelial dysfunction ENDOTHELIN COCRYSTALS Nanorods BOSENTAN ANDROGRAPHOLIDE

Bosentan Is Associated with a Reduction in Right Ventricular Systolic Pressure N-Terminal Pro-Hormone B-Type Natriuretic Peptide Levels in Young Patients with Pulmonary Hypertension: 《Open Journal of Pediatrics》2023年第1期32-42,共11页Lily M. Landry Andrew C. Burks Onyekachukwu Osakwe Jarrod D. Knudson Christopher L. Jenks; Pulmonary hypertension is a rare and potentially fatal disease in children if left untreated. Emerging therapies, including Bosentan, a dual endothelin receptor antagonist, have shown significant benefits in the adult...; 关键词：Pulmonary Arterial Hypertension Bronchopulmonary Dysplasia Endothelial Receptor Antagonist Congenital Heart Disease

D-Transposition of Great Arteries in a Primigravida of 35 Years Old-Case Report and Literature Review: 《Journal of Pharmacy and Pharmacology》2018年第7期674-678,共5页Ali Kassen Omais Camila Martines Mello Nathalia Suzan Camarao Martins Natália Regina Alécio Mettelo Diehl Alethéia Carpine Favini Schefer Felipe Amorim Zarour Julio Cesar de Oliveira Janice Lanzarin Gisele do Couto Oliveira; This is a case report with discussion of the maternal-fetal outcome of pregnant women with uncorrected transposition of the great arteries （TGA） associated with pulmonary arterial hypertension and a large ventricula...; 关键词：Transposition of great arteries congenital heart disease BOSENTAN PREGNANCY

Efficacy of Bosentan in Patients after Fontan Procedures：a Double-blind, Randomized Controlled Trial被引量：1: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第4期534-540,共7页尚小珂卢蓉张喜张长东肖书娜柳梅王斌董念国; supported by the National Natural Science Foundation of China(No.31330029); Fontan surgery is a widely used palliative procedure that significantly improves the survival period of patients with complex congenital heart disease（CHD）. However, it does not decrease postoperative complication r...; 关键词：Fontan procedure BOSENTAN PROGNOSIS pulmonary hypertension pulmonary vascular resistance

Salvianolic acid A attenuates vascular remodeling in a pulmonary arterial hypertension rat model被引量：14: 《Acta Pharmacologica Sinica》2016年第6期772-782,共11页Yu-cai CHEN Tian-yi YUAN Hui-fang ZHANG Dan-shu WANG Yu YAN Zi-ran NIU Yi-huang LIN Lian-hua FANG Guan-hua DU; Aim： The current therapeutic approaches have a limited effect on the dysregulated pulmonary vascular remodeling, which is characteristic of pulmonary arterial hypertension （PAH）. In this study we examined whether s...; 关键词：salvianolic acid A Dan Shen BOSENTAN MONOCROTALINE pulmonary artery hypertension vascular remolding APOPTOSIS BMPRII SMAD

Endothelin-1 Antagonist in the Management of Refractory Systemic Hypertension in Children with End Stage Kidney Disease: A Case Series: 《World Journal of Cardiovascular Diseases》2014年第5期217-224,共8页Jayanthi Chandar Wacharee Seeherunvong Carolyn Abitbol Chryso Katsoufis Alcia Edwards-Richards Teresa Cano Gastón Zilleruelo; Uncontrolled hypertension is a significant problem in children with end stage kidney disease. We studied 10 children on chronic hemodialysis who received the endothelin-1 receptor antagonist, bosentan as adjunctive th...; 关键词：CHILDREN END STAGE Kidney Disease Hypertension BOSENTAN

Antenatal use of bosentan and/or sildenafil attenuates pulmonary features in rats with congenital diaphragmatic hernia被引量：1: 《World Journal of Pediatrics》2014年第4期354-359,共6页María de Lourdes Lemus-Varela Amed Soliz Belinda Claudia Gómez-Meda Ana Lourdes Zamora-Perez José Manuel Ornelas-Aguirre Valery Melnikov Blanca Miriam Torres-Mendoza Guillermo Moisés Zúñiga-González; supported by grants from the Fondo de Fomento a la Investigación,Instituto Mexicano del Seguro Social(FOFOI-FIS,IMSS,2006/1A/I/031-FIS/IMSS/PROT/205);by Miami Children's Hospital&Sheridan Health Corporation.; Background:Lung hypoplasia,pulmonary persistent hypertension of the newborn and its morphological changes are the main features in congenital diaphragmatic hernia(CDH).This study was undertaken to investigate if anten...; 关键词：antenatal treatment BOSENTAN congenital diaphragmatic hernia pulmonary hypoplasia SILDENAFIL

Short-Term Drug-Drug Interaction between Sildenafil and Bosentan under Long-Term Use in Patients with Pulmonary Arterial Hypertension: 《Pharmacology & Pharmacy》2013年第7期542-548,共7页Sachiko Miyakawa Keiichi Odagiri Naoki Inui Akio Hakamata Takahiro Goto Shimako Tanaka Shinya Uchida Noriyuki Namiki Hiroshi Watanabe; Sildenafil and bosentan are often co-administered for pulmonary arterial hypertension (PAH) treatment. The plasma concentration of sildenafil can be decreased by half if co-administered with bosentan. Many patients ta...; 关键词：Drug-Drug Interaction Pulmonary ARTERIAL Hypertension SILDENAFIL BOSENTAN PHARMACOKINETICS

Bosentan and antiretroviral therapy in an HIV/HBV/HCV coinfected Chinese patient with HIV-related pulmonary arterial hypertension被引量：2: 《Chinese Medical Journal》2013年第6期1197-1198,共2页WANG Mou-yue LIU Huan; To the editor： Pulmonary arterial hypertension （PAH） is an infrequent but nevertheless, serious life threatening complication of human immunodeficiency virus （HIV） infection. People infected with HIV have a high ...

Simple Estimation of Bosentan in Tablet Formulation by RP-HPLC: 《American Journal of Analytical Chemistry》2012年第11期715-718,共4页Selvadurai Muralidharan Jaya Raja Kumar; A simple, precise, and accurate method is developed and validated for the analysis of Bosentan tablet formulation. The method has shown adequate separation of the ingredients from Tablets. Separation was achieved on a...; 关键词：ESTIMATION VALIDATION RP-HPLC BOSENTAN

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