铜(Ⅱ)的5-氧-N-亚水杨基乙醇胺螯合物的合成与抑菌活性  

SYNTHESIS AND ANTIBACTERIAL ACTIVITIES OF CHELATES OF 5-CHLORO-N-SALICYLIDENE ETHANOLAMINE WITH COPPER(Ⅱ)

作　　者：柳翠英[1] 李忠[1] 赵全芹[1] 王德凤[1] 于爱华[1] 

机构地区：[1]山东医科大学药学系,济南250012

出　　处：《华西药学杂志》1997年第3期174-175,共2页West China Journal of Pharmaceutical Sciences

摘　　要：合成了5-氯-N-亚水杨基乙醇胺希夫碱及其与铜（Ⅱ）的四种新螫合物，其组成与结构由元素分析、红外光谱和原子吸收所表征。初步抑菌试验表明这些化合物对多种细菌有明显的抑菌活性。The chelates of 5-chloro-N-salicylidene ethanolamine Schiff base with Copper (Ⅱ)have been synthesized and characterized by elementary analysis,infrared spectra and atomic absorption. These chelates are new metal complexes of Schiff base type. They have been tested for their antibacterial activities. The results slowed that all the chelates displayed obvious antibacterial activities in the primary treatment of many types of bacteria.

关 键 词：亚水杨基乙醇胺 螯合物 抑菌活性 铜 

分 类 号：TQ463.6[化学工程—制药化工] R978[医药卫生—药品]