中低度近视眼高阶像差与低对比度视力相关性研究  

Correlation of ocular high-order aberration with low contrast visual acuity in low and moderate myopic eyes

作　　者：程振英[1] 褚仁远[1] 周行涛[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海市200031

出　　处：《眼科新进展》2008年第1期46-48,共3页Recent Advances in Ophthalmology

基　　金：上海市科委重点实验室项目基金资助(编号:2005DZ22325)~~

摘　　要：目的探讨中低度近视眼高阶像差与低对比度视力的关系。方法对65例65眼中低度近视患者,用WASCA波前像差仪测眼高阶像差,对瞳孔直径6mm时总高阶像差、各阶像差和各项Zernike函数（C6～C14）的均方根进行分析。用多功能电子视力测量仪测量亮、暗环境中对比度为10%和5%的最佳矫正视力。用多元线性回归分析眼高阶像差与各低对比度视力间的相关关系。结果眼总高阶像差与各低对比度视力间的直线相关关系均有显著统计学意义（P〈0.01）。在第3、4阶像差中,第3阶像差与各低对比度视力间的直线相关关系有显著统计学意义（P〈0.01）;第4阶像差与各低对比度视力间的直线相关关系无统计学意义（P〉0.05）。在C6～C14项Zernike函数中,水平慧差与各低对比度视力间的直线相关关系有显著统计学意义（P〈0.01）,其余Zernike函数（如球差、垂直慧差）与各低对比度视力间的直线相关关系均无统计学意义（P〉0.05）。结论中低度近视眼的水平慧差与低对比度最佳矫正视力有关。Objective To investigate the relationship between ocular high-order aberration and low contrast visual acuity in low and moderate myopic eyes.Methods High order aberration of 65 subjects （65 eyes） with low and moderate myopia were measured with WASCA wavefront analyzer.Root mean square （RMS） of the total high order aberration at 6mm pupil diameter,each order aberration and each Zernike coefficients were recorded for analysis.Best corrected visual acuity at 10% and 5% contrast level under photopic and mesopic condition were measured using computer generated mutifunction visual acuity analyzer.Mutiple linear regression was used to analyze the relation between ocular high-order aberrations and low contrast visual acuity.Results Mutiple linear regression analysis revealed that RMS of total high order aberration was significantly correlated with visual acuity at every low contrast level（P〈0.01）.RMS of the 3rd aberration was significantly correlated with visual acuity at every low contrast level（P〈0.01）,but RMS of the 4th aberration was not（P〉0.05）.Horizontal coma aberration was significantly correlated with visual acuity at every low contrast level（P〈0.01）,but the other Zernike aberrations including spherical aberration and vertical coma aberration was not（P〉0.05）.Conclusion This study suggests that horizontal coma aberration in low and moderate myopic eyes was significantly correlated with best corrected visual acuity at low contrast.

关 键 词：近视 高阶像差 低对比度视力 

分 类 号：R778[医药卫生—眼科]