子宫内膜癌85例临床分析  

Clinical analysis of 85 cases of endometrial carcinoma

作　　者：高敏[1] 蒋国庆[1] 燕鑫[1] 王文[1] 安娜[1] 高雨农[1] 

机构地区：[1]北京大学临床肿瘤学院,北京肿瘤医院暨北京市肿瘤防治研究所妇科,100036

出　　处：《中国妇产科临床杂志》2008年第1期16-17,70,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的探讨子宫内膜癌的临床特点及处理原则。方法回顾性分析1996年9月～2005年9月间北京大学临床肿瘤学院妇科收治的85例子宫内膜癌患者的临床资料、诊治经过及随访结果。结果单纯因腹腔冲洗液细胞学检查阳性导致手术病理分期由Ⅰ期升至Ⅲa期者6例,随访2年,未见复发。而同期因肿瘤侵犯子宫浆膜面或附件所诊断的Ⅲa期10例患者中,术后复发3例,因例数较少,未行统计学分析。13例侵及脉管者4例复发,复发率为30.8%,明显高于未侵及脉管者(3/39,P=0.046);复发患者中,68.8%于术后2年内发生。结论子宫内膜癌的复发与脉管浸润、手术病理分期及组织学分级有关;单纯因腹腔冲洗液阳性导致的Ⅲa期患者预后好于同期别的其他患者。Objective To analyze the clinical characteristics of endometrial carcinoma and to explore its prognosis. Methods The medical charts and follow - up records of 85 cases of endometrial carcinoma were reviewed and analyzed retrospectively. Results No recurrence was found in the group of 6 patients whose stage increased from Ⅰ to Ⅲa because of positive peritoneal lavage by 2 - year follow - up, however 3 out of 10 recurred with stage Ⅲa because of cancer invasion of uterine serosa or annex. Recurrent rate was higher in those with vascular invasion than those without （4/13 vs. 3/39, P=0. 046）. Most of recurrent （68.8%） occurred within 2 years postoperatively. Conclusions The recurrence of endometrial carcinoma is related to the operative - pathological stage and histological grade. The prognosis of Ⅲa stage patients with single positive peritoneal lavage is better than the other patients at the same stage.

关 键 词：子宫内膜癌 复发 腹腔冲洗液 脉管浸润 

分 类 号：R737.33[医药卫生—肿瘤]