嗅神经母细胞瘤的MRI表现  

MRI Findings of Olfactory Neuroblastoma

作　　者：毛永征[1] 王振常[1] 杨本涛[1] 常青林[1] 陶建华[1] 

机构地区：[1]首都医科大学附属北京同仁医院放射科,北京100730

出　　处：《实用放射学杂志》2008年第1期13-16,共4页Journal of Practical Radiology

摘　　要：目的探讨嗅神经母细胞瘤的MRI诊断价值。方法对14例经病理证实的嗅神经母细胞瘤MRI资料进行回顾性分析。结果14例中10例肿块中心位于鼻腔顶部的中后方,1例位于鼻腔顶部的前方,1例占据整个鼻腔,1例位于上颌窦,1例位于鼻咽部。8例形态不规则,边界不清;6例形态规则,边界较清楚。肿块信号多不均匀,在T1WI以等或略低信号为主,T2WI以等或稍高信号为主,明显强化。肿瘤侵犯筛窦12例、颅内11例、眼眶10例、蝶窦5例、鼻中隔上部5例、上颌窦4例、额窦3例、翼腭窝2例、鼻咽2例、视神经管2例、斜坡1例、鼻泪管1例、面颊部1例。结论鼻腔顶部的中后方肿块并穿越筛板侵犯嗅沟区,是嗅神经母细胞瘤的特征性改变。MRI可准确显示肿瘤的部位和侵犯范围,可为临床分期和制订治疗方案提供依据。Objective To discuss the value of MRI in diagnosing olfactory neuroblastoma（ONB）. Methods MRI findings of ONB proved by pathology in 14 cases were analyzed retrospectively. Results The mainly focus of lesions were located in the middle - posterior part of the upper nasal cavity in 10 cases and the anterior part in one case, 1 occupied the whole nasal cavity,in the maxillary sinus and in the nasopharynx in one case respectively. Eight lesions were irregular in shape with poor - defined margin, while the other 6 were regular with well - defined margin. The signal intensity of the lesions was often heterogeneous ,isointense or slightly hypointense on the T1 WI, isointense or mildly hyperintense on the T2WI. All lesions enhanced markedly after contrast administration. The lesions invaded the ethmoid sinu- ses in 12 cases, intracranial structures in 11, orbits in 10 , sphenoid sinuses in 5 , upper nasal septa in 5 , maxillary sinuses in 4, frontal sinuses in 3 , pterygopalatine fossae ,nasopharynxes and optic canals in 2 respectively, clivus, nasolacrimal duct and cheek in 1 respectively. Conclusion ONB characteristically originated in the middle - posterior part＇of the upper nasal cavity, extending through the cribriform plate into the olfactory groove. MRI can accurately show the tumor and its extension, thus providing information for clinical stage and the therapeutic procedure for it.

关 键 词：鼻腔 神经母细胞瘤 嗅神经 磁共振成像 

分 类 号：R739.62[医药卫生—肿瘤] R445.2[医药卫生—临床医学]