宫颈小细胞癌诊治进展  

Advances in Diagnosis and Treatment of Cervical Small Cell Carcinoma

作　　者：韦德英[1] 谭迎春[2] 刘鸣[1] 汤春生[1] 

机构地区：[1]山东省立医院妇产科,济南市250021 [2]山东大学千佛山医院妇产科

出　　处：《中国肿瘤临床》2008年第1期57-59,共3页Chinese Journal of Clinical Oncology

摘　　要：宫颈小细胞癌(smallcellcarcinomaofcervix,SCCC)属神经内分泌癌,是一种少见的高度恶性妇科肿瘤,预后较宫颈鳞、腺癌差,治疗方案亦有差异。其诊断建立在组织病理形态学基础上,以形态大小均匀一致的小、圆肿瘤细胞(燕麦细胞)为特征,免疫组织化学标记有助于诊断。治疗以综合治疗为主,术后化疗采用VAC/PE/TP方案可明显改善患者预后。本文对其临床、病理特点及诊断治疗方法新进展等方面做一综述,以提高对本病的认识,提高诊断符合率,改善治疗及预后。Small cell carcinoma of cervix （SCCC） is a rare and high-grade malignant neuroendocrine tumor. With poorer prognosis than cervical squamous cancer and adenocarcinomna, it should be treated differently. Diagnosis is based on presence of small and round cancer cells （oat cells）, and confirmed by immunnhistological staining. Combined therapy is recommended. Postoperative platinum/etoposide （PE）, vineristine/adriamycin/cyclophosphamide（VAC）, taxel/carboplatin （TP） chemotherapy can improve the prognosis. To understand SCCC better, we review its clinical charaeteristics, pathological features and especially the recent advances in the diagnosis and treatment of this disease.

关 键 词：宫颈肿瘤 小细胞癌 神经内分泌肿瘤 

分 类 号：R737.33[医药卫生—肿瘤] R735[医药卫生—临床医学]