白刺果对大鼠血清中谷胱甘肽过氧化物酶和丙二醛的影响  

EFFECTS OF NITRARIA TANGUTOUM BOR OF INNER-MONGOLIA ON GSH-PX AND MDA IN SERUM OF THE RATS

作　　者：和彦苓[1] 许秀举[1] 刘永华[1] 戈娜[1] 邢少姬[1] 吴刚[1] 

机构地区：[1]内蒙古科技大学包头医学院,内蒙古包头014010

出　　处：《食品研究与开发》2008年第2期12-14,共3页Food Research and Development

基　　金：内蒙古自然科学基金资助(200308060209)

摘　　要：研究白刺果对大鼠血清中谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-PX)活性及丙二醛(malondialdehyde,MDA)含量的影响。以成年Wistar大鼠40只分为4组:对照组、白刺果高剂量组、白刺果中剂量组、白刺果低剂量组,饲养5周后,测定其血清中GSH-PX的活性和MDA的含量。结果:白刺果高剂量组与对照组相比血清中GSH-PX的活性显著提高(P<0.01);而其他两组与对照组比较统计学检验无显著性差异(P>0.05)。对于血清中MDA含量测定表明3种剂量组与对照组比较都无显著性差异(P>0.05)。结论:高浓度的白刺果可增强大鼠血清中谷胱甘肽过氧化物酶活性。To study the effects of Nitraria tangutoum Bor on activities of glutahione peroxidase （GSH-PX）and malondialdehyde（ MAD ）levels in serum of the rats. Forty wistar＇s rats were distributed into 4 groups with 10 rats in each. Group 1 is control group, group 2 with high dosage of Nitraria tangutoum Bor, group 3 with middle dosage of Nitraria tangutoum Bor, group 4 with low dosage of Nitraria tangutoum Bor. GSH-PX activities and MDA levels in serum were measured after 5 weeks. Results：The activities of GSH-PX in high dosage group of Nitraria tangutoum Bor is increased significantly than those of the control group （P〈0.01）, there are no marked difference of GSH-PX levels in serum （P〉0.05） of other experimental observation groups. Meantime the control group comparing with experimental observation groups was no marked difference of the MDA levels in serum （P〉0.05）. Conclusion： It was suggested that Nitraria tangutoum Bor high dosage groups could improve the activities of GSH-PX in serum of the rats.

关 键 词：白刺果 谷胱甘肽过氧化物酶 丙二醛 

分 类 号：R285[医药卫生—中药学]