依诺肝素钠细菌内毒素检查可行性探讨  

Feasibility of detection of bacterial endotoxin in enoxaparin sodium

作　　者：郑霞[1] 赵毓梅[1] 

机构地区：[1]海南省药品检验所,海南海口570216

出　　处：《中国热带医学》2008年第2期297-298,共2页China Tropical Medicine

摘　　要：目的建立依诺肝素钠的细菌内毒素检查方法。方法根据中国药典2005年版二部附录细菌内毒素检查法进行。结果依诺肝素钠在浓度为25.0IUAXa/ml时对细菌内毒素检查法无干扰。结论依诺肝素钠按限值L=0.01EU/IUAXa进行细菌内毒素检查是可行的。Objective To establish a method for test of bacterial endotoxin with enoxaparln sodium. Methods The experiment was carried out according to China Pharmacopeia in 2005 Edition （second part）. Results Enoxaparin sodium at diluted concentration of 25.0IUAXa/ml did not interfere with the results of test of bacterial endotoxin. Conclusion Enoxaparin sodium with L= 0.01EU/IUAXa can be used in bacterial endotoxin test.

关 键 词：依诺肝素钠 细菌内毒素检查 干扰试验 

分 类 号：R331[医药卫生—人体生理学]