三七总皂苷对急性脑梗死患者血清sICAM-1的影响  

Influence of panax notoginseng saponins on serum sICAM-1 in patients with acute cerebral infarction

作　　者：严秋凤[1] 谭佩珍[1] 刘秋庭[1] 周爱华[1] 徐燕[1] 周妮娜[1] 杨倩[1] 

机构地区：[1]湖南省第二人民医院神经内二科,长沙410007

出　　处：《中国实用神经疾病杂志》2008年第2期56-57,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的观察不同的药物治疗对急性脑梗死患者血清可溶性细胞间黏附分子-1(sICAM-1)的影响。方法84例患者分为治疗组44例和对照组40例,治疗组应用三七总皂苷,对照组应用维脑路通,采用双抗体酶联免疫吸附法(ELISA)分析。结果2组患者治疗后血清sICAM-1含量均降低,治疗组下降更显著。结论三七总皂苷对急性脑梗死患者血清中异常升高的sI-CAM-1有明显降低作用,其疗效优于对照组,差异有统计学意义(P<0.05)。Objective To study the influence of different medicine treatments on serum soluble intercellular adhesion molecule-1 （slCAM-1） in patients with acute cerebral infarction. Methods Some 84 cases were divided into two groups., controlled group（44 eases） and eompared group（40 cases）. Controlled group was applied panax notoginseng saponins, compared group was applied weinaolutong. Double anti-body enzyme-linked immuno sorbent assay was used. Results After treatment, serum slCAM-1 was decreased in both groups,but the controlled group decreased significantly. Conclusion Panax notoginseng saponins has a obvious effect on abnormally elevated serum sICAM-1 in patients with acute cerebral infarction. Its curative effect is superior to that of weinaolutong. There is a significant difference between them（P〈0.05）.

关 键 词：三七总皂苷 脑梗死 可溶性细胞间黏附分子-1 

分 类 号：R743.33[医药卫生—神经病学与精神病学]