吉林省砷中毒地区先天畸形调查  

Investigation of congenital deformity in the drinking water endemic arsenism area in Jilin Province

作　　者：卢振明[1] 佟建冬[1] 张秀丽[1] 刘忠杰[1] 梁宝成[2] 刘洪 曹世明[2] 李军[2] 寇百洲 杨德民 

机构地区：[1]吉林省地方病第一防治研究所,白城137000 [2]通榆县疾病预防控制中心 [3]白城市疾病预防预防控制中心

出　　处：《中国地方病防治》2008年第1期1-2,共2页Chinese Journal of Control of Endemic Diseases

基　　金：联合国儿童基金会资助课题(2004)

摘　　要：目的探讨饮水型砷中毒对出生缺陷或先天畸形的影响。方法采取横断面与回顾性调查相结合、整群抽样、定点定时入户的调查方法。结果横断面调查病区及高砷区畸形率为6.69‰,非高砷区畸形现患率为2.28‰,二者比较无差异。回顾性调查砷中毒病区及高砷区畸形率为6.33‰,非高砷区畸形率4.2‰,二者比较无差异。畸形中以脑发育不全、斜视、唇裂多见。结论病区及高砷区组出生缺陷的发生率高于对照组,但差异并不显著,说明高砷可能对孕妇及胎儿会有一定的影响。Objective To explore the influence of drinking water endemic arsenism on congenital deformity. Methods Cross sectional survey and retrospective investigation were used . Results The cross sectional Survey showed that the prevalence rate of congenital deformity was 6.69‰ in the arsenism areas and high arsenic areas and 2.28‰ in the non - high arsenic areas . The retrospective investigation showed that a deformity rate of 6.33‰ was ohserved in the arsenism areas and high arsenic areas and 4. 12 ‰ in the non - high arsenic areas . Conclusions The rate of congenital deformity in the arsenism areas and high arsenic areas is higher than that in the non - high arsenic areas, but there are not significant differences between them. Explain the high arsenic possibly having influence to pregnant woman and embryos.

关 键 词：饮水型砷中毒 先天畸形 调查 

分 类 号：R599.9[医药卫生—内科学]