牙槽外科中采用异种脱细胞真皮基质修复口腔软组织浅层缺损的效果  

Effects of an acellular dermal matrix allograft on the healing of shallow oral soft tissue defects

作　　者：侯锐[1] 胡开进[1] 姚小虎 王新木[1] 刘桂才[1] 周宏志[1] 张莉[1] 

机构地区：[1]西安第四军医大学口腔医学院口腔颌面外科,710032 [2]烟台正海生物技术有限公司

出　　处：《实用口腔医学杂志》2008年第1期111-114,共4页Journal of Practical Stomatology

摘　　要：目的:评价在牙槽外科中采用正海生物膜(一种异种脱细胞真皮基质)修复口腔软组织浅层缺损的效果。方法:选择28例口腔软组织浅层缺损患者应用正海生物膜进行治疗,术后进行随访,观察生物膜成活情况,颜色、质地以及对患者的影响等,并进行统计分析。结果:术后生物膜全部成活,术后2周成活面积达(97.10±6.20)%;1个月生物膜收缩率为(9.68±11.16)%。受植床表面颜色多为粉红,质地柔软,瘢痕轻微;患者进食不受影响,未出现明显局部或全身反应。术前术后实验室检查项目无显著性差异。结论:应用正海生物膜治疗牙槽外科中常见口腔内软组织浅层缺损安全有效,值得临床推广使用。Objective： To evaluate the effects of Zhenghai Bio-Membrane, an acellular dermal matrix allograft, on healing of shallow oral soft tissue defects. Methods：Twenty-eight patients who suffered shallow oral soft tissue defects were treated with Zhanghai Bio-membrane. The conditions of the bio-membrane, such as survival rate, color, texture were observed after implanting. The effects on the subjects were also observed. Results： All the Bio-membrane survived after implanting. The percentage of take area was （97.10 ± 6.20）% two weeks after operation. The percentage of shrinkage area was （9.68 ± 11.16 ）% one month after operation. Most of the operation sites were pink and soft, with few scars. The patients could take food without difficulty. Furthermore, there were no significantly local or general inflammatory reaction. There were also no significant differences on the common examination between pre-operation and post-operation. Conclusion： Healing of shallow oral soft tissue defect by the Zhenghai Bio-Membrane is safe and effective.

关 键 词：生物膜 修复 口腔软组织 浅层缺损 

分 类 号：R782[医药卫生—口腔医学]