侵袭性垂体腺瘤的伽玛刀治疗  

Gamma knife radiosurgery for invasive pituitary adenoma

作　　者：梁舜尧[1] 邓印辉[1] 

机构地区：[1]广州医学院第二附属医院广州伽玛刀治疗研究中心,广东广州510260

出　　处：《中国微侵袭神经外科杂志》2008年第1期13-14,共2页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨伽玛刀治疗侵袭性垂体腺瘤的疗效。方法对临床确诊的126例侵袭性垂体腺瘤病人行Siemens Symphony 1.5TMR扫描定位,应用ElektaTPS设计治疗规划,采用Leksell-B型伽玛刀实施治疗。结果随访4～99个月。影像学检查显示肿瘤控制率为95.2%(120例),临床症状改善率为92.9%(117例),内分泌改善率为91.7%(33例),复发率为0.8%(1例)。无远期并发症。结论伽玛刀可作为侵袭性垂体腺瘤的首选治疗方法,疗效较好。Objective To explore the result of Gamma knife radiosurgery for invasive pituitary. Methods One hundred and twenty-six cases of invasive pituitary adenoma were located by Siemens Symphony 1.5 T MR, then treated by Leksell-B type Gamma knife unit. Results All the patients had a follow-up of 4-99 months respectively. The tumor control rate was 95.2% （120 cases）, clinical symptom improvement rate was 92.9% （117 cases）, endocrine improvement rate 91.7% （33 cases）, and the recurrence rate 0.8% （1 case）. No complication occurred. Conclusion Gamma knife radiosurgery can be the first choice of the invasive pituitary adenoma, and may have good therapeutic effect.

关 键 词：侵袭性垂体腺瘤 放射外科手术 

分 类 号：R736.4[医药卫生—肿瘤] R815.2[医药卫生—临床医学]