早期宫颈癌术后辅助治疗疗效分析  

Therapeutic effect of adjuvant treatment for early stage cervical carcinoma after radical surgery

作　　者：杨卫卫[1] 康婷[1] 白东玫[1] 王海英[1] 

机构地区：[1]延安大学医学院附属医院肿瘤科,陕西延安716000

出　　处：《现代肿瘤医学》2008年第2期274-276,共3页Journal of Modern Oncology

摘　　要：目的:研究宫颈癌术后辅助治疗的选择与疗效。方法:回顾性分析159例宫颈癌根治术后辅助放疗加或不加化疗的患者治疗效果,选取130例同期行宫颈癌根治术的Ⅰb期及Ⅱa期未作术后辅助治疗患者作为对照组,进一步分析宫颈癌预后因素。159例患者中有87例放疗化疗综合治疗,72例单纯放疗。结果:289例患者总的5年生存率为89.3%,(单纯放疗组5年生存率88.9%,放疗化疗综合治疗5年生存率为89.7%),对照组5年生存率72.9%。两者差异有显著性(P<0.05)。结论:宫颈癌术后辅助治疗尤其对于盆腔淋巴结转移者有意义,临床和术后病理分期是术后辅助治疗的选择与疗效最主要的影响因素,不同病理类型及分级的宫颈癌术后辅助治疗可有不同的选择。Objective：To evaluate therapeutic effect of adjuvant treatment for stage Ⅰ b- Ⅱ a cervical carcinoma after radical surgery. Methods： The treated group：159 patients with stage Ⅰ b and Ⅱa cervical carcinoma after radical surgery,received adjuvant radiotherapy and/or chemotherapy. Of this patients, 87 received radiotherapy and chemotherapy,72 received radiotherapy only. The control group： 130 patients with stage Ⅰ b, Ⅱ cervical carcinoma after radical surgery without any treatment. Results ： The overall 5 - year survival rate for 289 patients was 89.3 % , for the radiotherapy group and the radio -chemeotherapy group,the 5 -year survival rates were 88.9 % and 89.7%. The control group 5 - year survival rates was 72.9%. The therapeutic effect in the treated group was much better than that in the control group（P 〈 0.05 ）. Conclusion： The therapeutic effect of adjuvant treatment for early stage cervical carcinoma after radical surgery may be of important value, The important risk factors for cervical carcinoma were clinical stage, pathological type, number of lymphnodes metastases.

关 键 词：宫颈癌 化疗联合放疗 单纯放疗 根治术 术后辅助治疗 

分 类 号：R737.33[医药卫生—肿瘤]