参芪扶正注射液联合VAD方案治疗多发性骨髓瘤临床研究  

Comparison of VAD regimen plus Shen-Qi-Fu-Zheng injection with VAD regi men alone in patients with multiple myeloma

作　　者：姜志平[1] 陈方平[1] 

机构地区：[1]中南大学湘雅医院血液科,湖南长沙410008

出　　处：《现代肿瘤医学》2008年第2期298-299,共2页Journal of Modern Oncology

摘　　要：目的:比较参芪扶正注射液联合VAD方案或单独使用VAD方案治疗多发性骨髓瘤的疗效和不良反应,及对于患者生活质量的影响。方法:入选的患者随机分为2组,治疗组采用VAD方案化疗加用参芪扶正注射液,对照组单用VAD方案化疗,并分别比较两组的临床疗效、不良反应及生活质量。结果:两组近期疗效无显著性差异,但是治疗组的不良反应发生率较对照组轻,治疗组对生活质量的改善优于对照组。结论:参芪扶正注射液联合VAD方案治疗多发性骨髓可以减低患者不良反应,有助于提高生活质量。Objective：To compare the clinical outcome and safety of VAD regimen plus Shen - Qi - Fu - Zheng injection with VAD regimen alone in patients with multiple myeloma, and the change of quality of life of patients with multiple myeloma. Methods： Total of 46 patients with multiple myeloma were divided randomly into 2 groups. Then VAD regimen plus Shen - Qi - Fu - Zheng or VAD regimen alone were given, respectively. Results： Both groups had similar clinical outcome, but VAD regimen plus Shen - Qi - Fu - Zheng seemed to have less side reaction and better quality of life. Conclusion： Shen - Qi - Fu - Zheng injection plus VAD regimen can help to reduce side reaction and improve quality of life of patients with multiple myeloma.

关 键 词：参芪扶正注射液 VAD方案 多发性骨髓瘤 

分 类 号：R733.3[医药卫生—肿瘤]