自体肋骨-肋软骨移植颞下颌关节重建术后的近期组织学变化  

A preliminary report of histological study on TMJ reconstruction with autogenous costochondral graft

作　　者：樊瑞彤[1,2] 王翰章[1,2] 王大章 

机构地区：[1]遵义医学院口腔系 [2]华西医科大学口腔医学院

出　　处：《中华口腔医学杂志》1997年第4期224-226,共3页Chinese Journal of Stomatology

基　　金：国家教委博士点专项基金

摘　　要：为从组织学角度考察颞下颌关节重建术后，移植骨的生物学行为及受植床的反应情况，作者采用纯种猪自体肋骨－肋软骨移植行单侧颞下颌关节重建术，动态观察术后近期受植床及移植骨的组织学变化情况。结果提示自体移植骨与其周围软组织愈合良好。引导和诱导受植床来源的间充质样细胞，在其表面和内部分化成骨，并呈逐渐取代移植骨的趋势。此外，在移植骨外较厚的软组织内可见活跃的成骨活动。说明关节重建术后，移植骨作为支架诱导成骨，以及受植区存在的某种成骨机制。将共同构成新生髁突，并决定着髁突的生长。To study histologically the biological behaviour of the grafts and the reactions in the receipt area after reconstruction of temporomandibular joint (TMJ), we have reconstructed experimentally removed TMJs on purebred juvenile pigs by transplanting autogenous costo chondral grafts. The findings of continuously survey of histologic changes in the receipt areas and the grafts showed that autogenous grafts healed well with the surrounding soft tissues, and induced the mesenchymal like cells from the receipt region, rather than the periosteal cells which might be left, to differentiate and ossify both within and at the surface of them, and they themselves were gradually replaced by the new formed bone; and that active osteogensis could also be seen within the thick tissues far from the graft, which could not be the result of graft′s induction. It may be concluded that the new bone, both from the induction of the graft which acts as a framework and somehow from the outside tissues, reconstructs the new condyle and determines the postsurgical growth of the mandible.

关 键 词：颞下颌关节 重建术 骨移植 组织学 

分 类 号：R782.605[医药卫生—口腔医学]