动脉内溶栓治疗急性缺血性脑卒中的临床分析  

Treament of acute ischemic stroke patients with intra-arterial fibrinolysis

作　　者：江卫[1] 沈晓文[1] 戴文卓[1] 孙杨[1] 孔岳南[1] 姚晴宇[1] 

机构地区：[1]南京医科大学附属无锡二院神经内科,214023

出　　处：《脑与神经疾病杂志》2008年第1期63-64,73,共3页Journal of Brain and Nervous Diseases

摘　　要：目的:探讨使用动脉内溶栓方法治疗急性缺血性脑卒中的效果。方法:回顾138例急性缺血性脑卒中患者,发病距接受治疗的时间为3～24h,采取超选择性动脉溶栓。结果:颈内动脉闭塞22例,大脑中动脉主干闭塞38例,大脑中动脉分支闭塞33例,大脑前动脉闭塞1例,椎基底动脉系统血管闭塞12支。脑血管造影未见异常32例。闭塞血管再通者,颈内动脉12例;大脑中动脉24例;大脑中动脉分支21例;椎基底动脉8例。8例患者因明显血管狭窄,治疗后予以球囊扩张,支架植入术。临床症状完全恢复或明显好转83例,溶栓后脑出血患者5例。结论:超选择动脉内溶栓是治疗急性缺血性脑卒中的有效方法。Objective： To evaluate the efficacy of intra-arterial fibrinolysis for acute thrombosis of cerebral vessels. Methods：138 patients with acute ischemic stroke, the duration from onset of symptoms to fibrinolysis were 3-24h. Resuits：22 occlusions were found in ICA, 38 in middle cerebral artery, 33 in branches of middle cerebral artery, 1 in anterior cerebral artery and 12 in vertebral-basal artery. No obvious abnormality was identified in 32 cases. 12 recanalizations were achieved in ICA occlutions, 24 in middle cerebral artery, 21 in the branches of middle cerebral artery, and 8 in vertebral- basal artery. 8 patients received angioplasty with balloon and/or stents for severe stenoses of vessels. The nervous system symptoms of 83 cases recoverd completely or satisfactorily. Complications.. S with the brain hemorrhage. Conclusion： Superselective intra-arterial fibrinolysis is a valuable therapeutic way for acute thrombosis of cerebral.

关 键 词：缺血性脑卒中 动脉溶栓 

分 类 号：R743.32[医药卫生—神经病学与精神病学]