28例原发性食管小细胞癌外科疗效分析  

Clinicopathologic observation and surgical treatment of primary small cell carcinoma of esophagus:analysis of 28 cases

作　　者：王海东[1] 邱阳[1] 吴蔚[1] 杨康[1] 熊刚[1] 廖克龙[1] 张伟[1] 王明荣[1] 曾会昌[1] 

机构地区：[1]第三军医大学西南医院胸心外科,重庆400038

出　　处：《重庆医学》2008年第4期353-354,共2页Chongqing medicine

摘　　要：目的探讨原发性食管小细胞癌的外科治疗效果。方法对28例接受手术治疗的原发性食管小细胞癌患者的疗效进行回顾性分析。结果按1997年新的国际食管癌TNM分期标准,Ⅰ期5例、Ⅱ期13例、Ⅲ期10例。手术后1、2、3年和5年生存率分别为50.0%、21.4%、10.7%、7.1%,最长生存者已达8年,中位生存期15个月。结论原发性食管小细胞癌恶性程度高、预后差,肿瘤的TNM分期仍是影响其疗效的重要因素。如何早期发现和对早期患者实施以手术为主的综合治疗是提高疗效的关键。Objective To summarize the experience in surgical treatment of primary small cell carcinoma（SCC） of esophagus. Methods 28 cases SCC of the esophagus undergone surgical treatment were analysed retrospectively. Results According to the New TNM Classification in Esophageal Carcinoma（1997）,within the 28 cases undergone surgical treatment, 5 cases were in stage Ⅰ,13 cases in stage Ⅱ and the other 10 cases in stage Ⅲ. The 1,2,3 and 5-year survival rate of them were 50.0%,21.4%,10, 7%, 7.1 % respectively; average 15 months. Conclusion SCC of esophagus is a kind of highly malignant neuroendocrine tumor with poor prognosis. The TNM staging and modality of operation are the important influencing factors in long-terra survivals. The survival term may be prolonged by early detection of the SCC,early surgical intervention and adjuvant multimodality treatments.

关 键 词：食管小细胞癌 手术 预后 

分 类 号：R735.1[医药卫生—肿瘤] R730.56[医药卫生—临床医学]