早期分子预警标志在宫颈癌前病变的应用  

Application of early molecular liiomarkers in cervical precancerous lesions

作　　者：贺其志(综述)[1] 陆惠娟(审校)[1] 杨雁(审校)[1] 

机构地区：[1]同济大学附属第一妇婴保健院病理科,上海200040

出　　处：《国际肿瘤学杂志》2008年第1期57-60,共4页Journal of International Oncology

摘　　要：宫颈癌是常见的妇科恶性肿瘤之一，从人乳头状瘤病毒感染宫颈到完全癌变常经过一段较长时间，因此对于宫颈癌前病变的诊断和筛查已成为预防和控制宫颈癌的重要方法。早期分子预警标志可以从分子水平来客观评估宫颈组织细胞的病变及晋级趋势，为宫颈癌前病变诊断和筛查提供有效的工具。Cervical carcinoma is one of the most common malignancies among women worldwide. On average,it takes long before a persistent human papillomavirus infection may ultimately ,via consecutive premalignant stages,lead to an overt cervical carcinoma. Therefore diagnosing and screening precursor lesions have become main measure in prevention and control of cervical cancer. Early molecular biomarkers could help identify cervical precursor lesions with an increased risk of malignant progression, and offer a valid tool to diagnosis and screening precursor lesions.

关 键 词：宫颈肿瘤 生物学标记 早期分子预警标志 癌前病变 诊断 筛查 

分 类 号：R737.33[医药卫生—肿瘤]