早期视觉诱发电位对眼外伤性视神经挫伤的诊治价值  

Value of diagnosis and treatment visual evoked potential in patients with optic nerve contusion following ocular damage

作　　者：王秀敏[1] 孙大山[1] 

机构地区：[1]安徽省宿州市立医院肌电图室,234000

出　　处：《蚌埠医学院学报》2008年第1期51-53,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨视觉诱发电位(visual evoked potential,VEP)在眼外伤性视神经挫伤中的诊治应用价值。方法:对36例临床诊断为外伤性视神经挫伤患者进行VEP测定,并与自身健侧眼或正常对照组进行对照。结果:36例中单眼挫伤32例,双眼挫伤4例,共40眼,VEP检查结果均有不同程度的异常,其中有1例2眼VEP波幅明显降低,单纯波幅异常降低者28例30眼,波幅降低伴有峰潜伏期延长者7例8眼。所有外伤性视神经挫伤与自身健侧眼和正常对照比较,P100波幅差异均有统计学意义(P<0.001和P<0.01);而P100峰潜伏期仅有7例稍有延长,与健侧眼差异有统计学意义(P<0.001),而与正常对照组比较差异无统计学意义(P>0.05)。结论:VEP对眼球钝挫伤后视神经损伤的检出有较高的敏感性,因此对于眼外伤性视神经挫伤中的早期诊断、疗效观察、预后评估有着重要价值。Objective：To explore the diagnosis and treatment value of visual evoked potential （VEP） for patients with optic nerve contusion following ocular damage. Metbods：VEP detection was performed in 36 patients with optic nerve contusion, and the result was compared with that of the contralateral healthy eyes and the normal control group. Results： VEP was determined in 40 eyes of 36 patients. Simple decrease of amplitude was found in 30 eyes of 28 patients and decrease of amplitude accompanied by the prolongation of latency in 8 eyes of 7 patients. There was significant difference in amplitudes of P100 among the damaged eyes, the contralateral healthy eyes and the normal group（P 〈0. 001 and P 〈0.01 ）. But the prolongation of latency of P100 was found in 7 patients. The difference was significant as compared with the healthy eyes （ P 〈 0. 001 ） , but no significant difference was noted in the latency of P100 as compared with the normal control group（ P 〉 0.05 ）. Conclusions： VEP is sensitive in the detection of optic nerve contusion following ocular damage. It is of value in early diagnosis and prognosis of optic nerve contusion following ocular damage.

关 键 词：眼损伤 视神经损伤 视觉诱发电位 波幅 诊断 鉴别 

分 类 号：R779.12[医药卫生—眼科] R774.6[医药卫生—临床医学]