正交试验优选乳病消片水提工艺  

Optimization of the Water Extracting Technology for Rubingxiao Tablet by Orthogonal Experiment

作　　者：荆晓红[1] 李红卫[1] 张和平 白贺明[3] 张晓琴[3] 

机构地区：[1]兰州大学第二医院药剂科,兰州市730030 [2]兰州三毛职工医院,兰州市730060 [3]兰州大学药学院,兰州市730000

出　　处：《中国药房》2008年第6期424-426,共3页China Pharmacy

摘　　要：目的:优选乳病消片的最佳水提工艺。方法:以出膏率和阿魏酸含量为考察指标,采用L9(34)正交试验方法优选乳病消片水提工艺。结果:最佳水提取工艺为A3B1C3D2,即用12倍量的水提取3次,每次0.5h,醇沉浓度为60%。结论:该工艺简便、快捷、稳定,可为生产提供理论依据。OBJECTIVE： To optimize the water extracting technology of Rubingxiao tablet .METHODS： The extracting technology of Rubingxiao tablet was optimized by orthogonal experiment with the yield of extractum and ferulic acid content as indices. RESULTS： The optimum extracting condition was AaB1C3D2,i .e. adding 12 times water and extracting 0.5 h/time for 3 times with 60% alcohol. CONCLUSION： The extracting technology for Rubingxiao tablet is simple and rapid with stable result, and it provided theoretical basis for the production of Rubingxiao Tablets.

关 键 词：乳病消片 阿魏酸 提取工艺 正交设计 

分 类 号：R283[医药卫生—中药学] R944.4[医药卫生—中医学]