增强核磁共振成像观察人眼羟基磷灰石义眼座的纤维血管化过程  

Enhanced MRI for observation of fibrovascularization of hydroxyapatite orbital implants in human eyes

作　　者：杜刚[1] 张虹[2] 李贵刚[2] 罗丰年[1] 孙叙清[1] 戴青[1] 张磊[1] 

机构地区：[1]解放军161医院眼科,中国湖北省武汉市430010 [2]华中科技大学附属同济医院眼科,中国湖北省武汉市430030

出　　处：《国际眼科杂志》2008年第2期330-332,共3页International Eye Science

摘　　要：目的:利用增强核磁共振(MRI)动态显像技术监测人眼羟基磷灰石(HA)义眼座完成纤维血管化的时间,对HA义眼座纤维血管化的MRI图像信息和量化数据进行研究,以证实MRI在评价义眼座纤维血管化程度方面的临床应用价值。方法:选择临床行眼内容物剜除术及一期HA义眼座植入术的患者15例15眼,自第1mo开始,每月1次,连续7次,每次均由放射科医师进行增强MRI的相关检查并计算MRI(VE/VHA)比值(VE为义眼座强化区体积,VHA为义眼座体积)。结果:人眼HA植入术后前6mo间依次比较MRI图像中VE/VHA比值显著增加,第6mo后不再增加。结论:核磁共振成像(MRI)可作为HA义眼座术后血管化程度监测的影像学依据。正常人眼眶内植入直径20mm的HA义眼座在6mo后完全纤维血管化。AIM： To monitor the time of fibrovascularization of hydroxyapatite （HA） orbital implants in human eyes by means of enhanced MRI dynamic imaging technology, and to confirm the clinical application value of MRI in assessment of fibrovascularization of HA orbital implants through studying related MRI information and data. METHODS： A total of 15 cases （15 eyes） who underwent enucleation and first stage HA orbital implants were enrolled in the study. Since the first month after the implantation, the related enhanced MRI examinations were performed by radiologist once a month for consecutive 7 times, and the values of VE/VHA were calculated. RESULTS： The values of VE/VHA in magnetic resonance imaging were significantly increased during the previous six months （ P 〈 0. 01 ） after HA orbital implants were accomplished in human eyes. However, the value of VE/ VHA in the seventh month was almost identical to that of the sixth month. CONCLUSION： MRI could be imaging evidence for monitoring the fibrovascularzation of HA orbital implants. HA orbital implants with the diameter of 20mm in normal human eyes could have complete fibrovascularization after six months.

关 键 词：核磁共振成像 羟基磷灰石 义眼座 纤维血管化 

分 类 号：R779.64[医药卫生—眼科] R445.2[医药卫生—临床医学]