Intestinal pseudo-obstruction:An uncommon condition with heterogeneous etiology and unpredictable outcome  

作　　者：Eugen Florin Georgescu Ion Vasile Reanina Ionescu 

机构地区：[1]Filantropia University Hospital from Craiova, Department of Internal Medicine 2, University of Medicine and Pharmacy of Craiova, Romania [2]Departmental Emergency University Hospital from Craiova, Department of General Surgery 2, University of Medicine and Pharmacy of Craiova, Romania

出　　处：《World Journal of Gastroenterology》2008年第6期954-959,共6页世界胃肠病学杂志（英文版）

摘　　要：Intestinal pseudo-obstruction (IPO) either acute or chronic is a condition including features of intestinal ileus in absence of mechanical obstruction. Our paper presents such a rare case of idiopathic IPO in a 53-year-old male patient with recurrent episodes of pseudo-obstruction, which were successfully resolved by anticholinesterase agents, motilin agonists or colonic decompression. However, the patient finally underwent total colectomy. Huge colonic dilatation was identified intraoperatorily, while histology showed a neuropathic variant of chronic intestinal pseudo-obstruction. Etiologic mechanisms and current therapeutic methods are reviewed in this paper, which concludes that IPO is a condition in which conservative treatment usually fails. Total colectomy with ileoanal pouch may be the only solution in these situations.Intestinal pseudo-obstruction （IPO） either acute or chronic is a condition including features of intestinal ileus in absence of mechanical obstruction. Our paper presents such a rare case of idiopathic IPO in a 53-year-old male patient with recurrent episodes of pseudo-obstruction, which were successfully resolved by anticholinesterase agents, motilin agonists or colonic decompression. However, the patient finally underwent total colectomy. Huge colonic dilatation was identified intraoperatorily, while histology showed a neuropathic variant of chronic intestinal pseudo-obstruction. Etiologic mechanisms and current therapeutic methods are reviewed in this paper, which concludes that IPO is a condition in which conservative treatment usually fails. Total colectomy with ileoanal pouch may be the only solution in these situations.

关 键 词：Intestinal pseudo-obstruction Anticholinesterase agents Motilin receptor agonists Colonoscopic decompression Total colectomy with ileoanal pouch 

分 类 号：R574[医药卫生—消化系统]