肿瘤患者医院感染特点及细菌耐药调查  

Investigation of Characteristics of Nosocomial Infection in Tumor Patients and Dynamic of Bacterial Resistance

作　　者：潘素琴[1] 

机构地区：[1]郑州市第二人民医院,郑州450006

出　　处：《药物流行病学杂志》2008年第1期30-32,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：目的:调查肿瘤患者医院内感染特点、常见病原菌和耐药情况。为临床医师合理使用抗菌药提供参考信息。方法:回顾性分析423例肿瘤患者发生医院感染情况,统计临床标本分离培养出的70株病原菌分类及药敏实验结果。结果:肿瘤患者医院感染率达16.55%,显著高于同期医院平均感染率7.37%。70株病原菌G^-占75.7%,G^+占15.7%,真菌占8.6%。铜绿假单胞菌、肺炎克雷伯菌、金黄色葡萄球菌、大肠埃希菌为主要感染菌,感染部位以呼吸道、泌尿道、手术切口为多见。结论:发生院内感染后,应常规作病原菌检查,并进行药敏试验,合理使用抗菌药。Objective： To investigate some characteristics of patients with nosocomial infection tumor, common pathogens and resistance to provide reference for reasonable clinical use of antibiotics. Method： The specimens of pathogens cultured from 423 cases of patients with tumor were retrospectively analyzed. Result： The rate of the hospital infection of tumor patients was 16.55%, significantly higher than 7.37%, the average infection rate in the same period. In the 70 pathogens, G^- accounted for 75.7%; G^＋, for 15.7%, and fungus, for 8.6%. Pseudomonas aeruginosa, Klebsiella pneumoniae, slaphylococcus aureus, escherichia coli bacteria as the main bacteria more commonly attacked the respiratory and urinary tracts and surgical incision. Conclusion： After nosocomial infections occurred, pathogens should be routinely checked, drugs, susceptibility tested and antibiotics, rationally used.

关 键 词：院内感染 病原菌 耐药性 

分 类 号：R73[医药卫生—肿瘤] R978.1[医药卫生—临床医学]