生物法生产山梨醇的研究进展  

Research Progress in the Biological Production of Sorbitol

作　　者：黄志华[1] 王宝光[2] 王海燕[2] 曹竹安[2] 

机构地区：[1]三明学院化学与生物工程系,福建三明365004 [2]清华大学化学工程系生物化工研究所,北京100084

出　　处：《三明学院学报》2007年第4期441-446,共6页Journal of Sanming University

基　　金：国家重点基础研究发展规划项目(973计划)(2003CB716007);福建省自然科学基金计划资助项目(2007J0287)

摘　　要：山梨醇在食品添加剂、医药及其他化工领域有着广泛的应用,随着需求量的增加,近年来山梨醇的生物法生产逐渐受到了关注。文章以产山梨醇菌株Zymomonas mobilis的主要特性为出发点,系统阐述了利用Z.mobilis生物法生产山梨醇的研究进展,并展望了未来的发展趋势和实现工业化生产需要解决的问题。Sorbitol is a polyol widely used in the food industry, pharmaceutical industry and other chemical related industries, not only as a sweetener but also as a humectant, texturizer, and softener. With the increasing demand of sorbitol, the biological production of sorbitol attracted a lot of attention in recent years. This article provides an overview on the biological prudction of sorbitol by the bacterium Zymomonas mobilis, the Z.moblilis is able to produce sorbitol and gluconic acid from fructose and glucose respectively, and this process is finished in a one-step reaction via a glucose-fructose oxidoreductase. Different methods which improve the productivity and economic efficiency for sorbitol production are discussed, besides, the properties, applications, market and possible industrial biological production are also discussed.

关 键 词：山梨醇 ZYMOMONAS mobilis 生物法生产 

分 类 号：TS202.3[轻工技术与工程—食品科学] TQ223.166[轻工技术与工程—食品科学与工程]