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作 者:张渺[1] 刘南平[1] 周宜容[1] 沙彦妮[1] 杨平[1]
机构地区:[1]宁夏医学院附属医院神经电生理科,宁夏银川750004
出 处:《河北医学》2008年第1期13-16,共4页Hebei Medicine
摘 要:目的:探讨癫痫儿童的认知学习状况。方法:采用学习障碍筛查量表(PRS)测量60例癫痫儿童和60例健康对照,并用丹麦维迪Keypoint诱发电位仪检测其事件相关电位P300。结果:①癫痫儿童PRS量表总分、言语得分及非言语得分均较正常儿童降低,差异有显著性(P<0.01);②癫痫儿童P300潜伏期较正常儿童延长,差异有显著性(P<0.01);③全面性发作组与部分性发作组比较,P300与PRS量表均未见显著性差异(P>0.05)。结论:本研究表明癫痫儿童存在学习障碍,PRS量表与P300可从不同角度反映癫痫儿童的认知学习状况。Objective: To explore the cognitive and learning status of epileptic children. Method: Auditory event - related potential (ERP) P300 and the Pupil Rating Scale Revised Screening for Learning Disabil- ities (PRS) were done separately in 60 children with epilepsy, and compared with 60 controls. Dantec keypoint electro -physiologic instrument was used to detect ERP P300. Results:(1)The total score , the verbal score and the nonverbal score of PRS in children with epilepsy showed significantly lower than the controls. (P 〈 0.01 ) ;(2)The latency of P300 in children with epilepsy showed significantly longer than the controls. ( P 〈0.01 ) ;(3)There was no significant difference of PRS or P300 between the children with generalized seizures and that with partial seizures ( P 〉 0.05 ). Conclusion: It is suggested that there is learning disability in children with epilepsy and it could be revealed by PRS or P300 from different side.
分 类 号:R742.1[医药卫生—神经病学与精神病学]
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