腺泡状软组织肉瘤的病理诊断  

Pathological diagnosis of alveolar soft part sarcoma

作　　者：石清涛[1] 耿敬姝[1] 冯占军[1] 

机构地区：[1]哈尔滨医科大学第三临床医学院病理科,黑龙江哈尔滨150081

出　　处：《哈尔滨医科大学学报》2008年第1期57-59,共3页Journal of Harbin Medical University

摘　　要：目的探讨腺泡状软组织肉瘤的组织病理学特征及鉴别诊断。方法对24例腺泡状软组织肉瘤进行组织病理学观察及免疫组织化学研究。结果24例腺泡状软组织肉瘤主要位于深部软组织内,由含有丰富嗜酸性颗粒状胞浆的大小一致的上皮样细胞构成,肿瘤细胞排列成实性巢和/或腺泡状结构,细胞巢之间有薄的窦状血管分隔,免疫组化未见有一致性阳性结果。结论腺泡状软组织肉瘤是一种主要累及青少年和年轻人的罕见肿瘤,结合临床和病理特征,可做出正确的病理诊断。但需与腺泡状横纹肌肉瘤、颗粒细胞瘤、副节瘤、血窦丰富的癌等相鉴别。Objective To review the morphologic features of alveolar soft part sarcoma and its differential diagnosis. Methods Clinical data and image findings were investigated. Histopathological and immunohistochemical changes were observed in 24 cases of alveolar soft part sarcoma. Results The ttanour most commonly occurred in the deep soft tissues of thigh. It was composed of large, uniform, epithelioid cells having abundant eosinophilic, granular cytoplasm arranged in solid nests and/or alveolar structures, separated by thin, sinusoidal vessels. It was extensively studied by using immunohistochemical methods, no consistent positive findings was shown. Conclusion Alveolar soft part sarcoma is a rare tumour affecting mainly adolescents and young adults. By combining with clinical and pathological features and excluding paraganglioma, granular cell tumour, alveolar rhabdomyosarcoma and some adenocarcinomas as differential diagnonsis, a correct pathological diagnosis can be made.

关 键 词：腺泡状软组织肉瘤 组织病理学 诊断 

分 类 号：R738.6[医药卫生—肿瘤]