原发性皮肤CD4^＋多形性小／中T细胞淋巴瘤1例临床病理观察并文献复习  

Primary cutaneous CD4^+ small/medium-sized pleomorphic T-cell lymphoma

作　　者：陈佳[1] 孙建方[1] 曾学思[1] 

机构地区：[1]中国医学科学院、中国协和医科大学皮肤病研究所病理科,江苏南京210042

出　　处：《临床皮肤科杂志》2008年第3期150-152,共3页Journal of Clinical Dermatology

摘　　要：报告1例原发性皮肤CD4+多形性小/中T细胞淋巴瘤。患者女,45岁。右膝右上方反复红斑、结节15年。组织病理检查示真皮全层及皮下脂肪层弥漫性结节性致密小到中等大淋巴样细胞浸润。细胞有异形,其间混杂少量炎性细胞,无亲表皮现象。免疫组化检查示全T抗原缺失的Th表型。诊断:原发性皮肤CD4+多形性小/中T细胞淋巴瘤。A case of primary cutaneous CD4^＋ small/medium-sized pleomorphic T-cell lymphoma is reported. A 45-year-old female presented with single red nodule on the right leg repeatedly for 15 years. The histopathologic examination showed diffuse and nodal infiltration of small/medium-sized pleomorphic T-cells in the dennis and subcutaneous layer, with admixture of some inflammatory cells. Immunohistochemistry study showed Th phenotype with loss of pan-T-cell markers. The diagnosis of primary cutaneous CD4^＋ small/medium-sized pleomorphic T-cell lymphoma was made.

关 键 词：淋巴瘤 皮肤 原发性 多形性 小/中T细胞 

分 类 号：R739.5[医药卫生—肿瘤]