维甲酸霜的一阶导数分光光度测定  

DETERMINATION OF TRETINOIN IN CREAM BY FIRST ORDER DERIVATIVE SPECTROPHOTOMETRY

作　　者：王茂义[1] 董亚琳[1] 阎正华[1] 姚美丽 

机构地区：[1]西安医科大学第一临床医学院

出　　处：《中国医药工业杂志》1997年第9期417-418,共2页Chinese Journal of Pharmaceuticals

摘　　要：采用一阶导数分光光度法测定维甲酸霜的含量，可消除基质的干扰。维甲酸的平均回收率为１００．０％，ＲＳＤ为１．１７％（ｎ＝６）。The first order derivative spectrophotometry was used to determine the tretinoin in cream. The absolute value of amplitude at 387 nm was linear with the concentration in the range of 2～6 μg/ml ( r =0.9999). The average recovery and RSD were 100.0% and 1.17%, respectively.

关 键 词：一阶导数 分光光度法 维甲酸 测定 

分 类 号：R977.21[医药卫生—药品]