氮化钛膜对纯钛表面细菌黏附能力的影响  

Influence of TiN coating on bacteria adhesion of Ti surface

作　　者：陈震[1] 梁峥嵘[2] 时光辉[1] 韩栋伟[1] 

机构地区：[1]同济大学附属口腔医院修复科,上海200072 [2]上海市长宁区中心医院口腔科,上海200336

出　　处：《同济大学学报（医学版）》2008年第1期37-40,共4页Journal of Tongji University(Medical Science)

基　　金：国家自然科学基金资助项目(30670570)

摘　　要：目的研究氮化钛膜形成对纯钛表面细菌黏附能力的影响。方法制作纯钛试件192件,随机选出96件,采用多弧离子镀法在其表面形成氮化钛膜,未镀膜纯钛为对照组,镀膜后纯钛为实验组。在实验组和对照组试件表面黏附血链球菌、粘性放线菌、白色念珠菌和金黄色葡萄球菌,分别进行细菌体外黏附实验。用菌落形成单位计数法统计分析在细菌黏附24、48、168 h时,各种细菌黏附量的变化。结果血链球菌、粘性放线菌、白色念珠菌和金黄色葡萄球菌在实验组表面黏附量较对照组表面黏附量显著减少(P<0.001)。结论纯钛表面氮化钛膜可抑制细菌黏附。Objective To study the influence of TiN coating on bacteria adhesion of clinically used Ti（TA2）. Methods One hundred and ninety-two pieces of TA2 were made and half of them was chosen randomly, and then TiN coating on the surface of them was made by multi-arc TiN coating technique as experimental group, while those of the non-coated were as control. Definite amounts of Streptococcus, Actinomyces viscosus, Candida albicans and Staphylococcus aureus were adhered onto the surfaces of TA2, and then the number of bacteria was assayed by means of clone forming unit （CFU）method at adhesion periods of 24,48,168 h respectively. Resuits At each period, all the number of the adhered Streptococcus, Actinomyces viscosus, Candida albicans and Staphylococcus aureus were reduced significantly in TiN coated TA2 group （P〈 0. 001 ）. Conclusion TiN coating may reduce bacterium adhesion on TA2.

关 键 词：纯钛 氮化钛膜 细菌黏附 

分 类 号：R781.05[医药卫生—口腔医学]