P-J综合征9例临床分析  

Clinical analysis of Peutz-Jeghers′ syndrome in 9 cases

作　　者：牛小平[1] 吴万春[1] 刘少锋[1] 何池义[1] 

机构地区：[1]皖南医学院附属弋矶山医院消化科,安徽芜湖241001

出　　处：《皖南医学院学报》2008年第1期46-47,共2页Journal of Wannan Medical College

摘　　要：目的：探讨黑斑息肉病（Peutz-Jeghers综合征,PJS）的临床特征、诊断及治疗。方法：统计2000-2005年收治的黑斑息肉病患者9例,对其临床表现及治疗对策进行分析。结果：内镜检查发现9例均有结、直肠息肉;小肠造影提示2例同时伴有胃和小肠息肉,4例伴小肠息肉;病理检查均为错构瘤;其中1例患者出现癌变,2例患者合并有腺瘤;2cm以下息肉在内镜下分批行电凝、电切治疗,1例癌变转外科手术。结论：内镜治疗对PJS疗效满意,同时鉴于PJS与恶性肿瘤密切相关,长期监测、定期复查有利于恶性病变的早期发现与治疗。Objective：To investigate the clinical manifestation of Peutz- Jeghers＇ syndrome for diagnosis and treatment. Methods ： The data of 9 patients confirmed with PJS from 2000 to 2005 in our hospital were collected for this retraspective study in terms of clinical features, diagnosis and treatment. Results： Endoscopic findings suggested that polyps of colorecturn were seen in 9 patients, in which 2 casecs were confirmed by visualization with gastric polyps and bowd polyps, and 4 cases with small bowel polyps. Pathological findings showed that the total 9 cases presented with hamartomas, in which 1 case was in presence of canceration and 2 cases were complicated with adenomatous polyps. Polyps of less 2 cm in diameter were undergone high frequency electro-coagulation or electro-resection by endoscopy and another 1 canccration case was referred to surgical operation. Conclusion ： Endoscopic therapy is sound to Peutz-Jeghers syndrome, but patients should be followed up and Examined regularly for early discovery and treatment since the disease may precede canceration.

关 键 词：P-J综合征 诊断 治疗 

分 类 号：R730.269[医药卫生—肿瘤]