短暂性脑缺血发作患者短期预后及相关危险因素的分析  

Analysis on short-term prognosis and correlated risk factors in patients with transient ischemic attack

作　　者：李浩军[1] 刘振国[1] 王文安[1] 李琳[1] 周永炜[1] 陈伟[1] 

机构地区：[1]上海交通大学医学院附属新华医院神经内科,200092

出　　处：《临床神经病学杂志》2008年第1期67-69,共3页Journal of Clinical Neurology

摘　　要：目的观察短暂性脑缺血发作(TIA)患者发病后90d的预后及其与各种危险因素的相关性。方法对61例临床确诊为TIA患者的90d随访及相关危险因素的资料进行分析;并对其头颅MR弥散加权成像(DWI)异常与正常患者的预后进行比较。结果61例中90d内发生各种严重血管事件10例(16.4%)。其中DWI异常者发生率为50%(8/16),正常者发生率为4.7%(2/43)。二者预后的比较差异有统计学意义(P<0.001);伴有糖尿病的TIA患者与预后存在相关性(OR值为7.6,P<0.05)。结论DWI异常、伴有糖尿病的TIA患者预后差。DWI的结果对TIA预后的判断有较大帮助。Objective To observe the prognosis 90 days after attack and the correlation among various risk factors in patients with transient ischemic attack （TIA）. Methods The data of 90 days follow up and related risk factors of 61 patients clinically diagnosed with TIA were analyzed. We also compared the prognosis of those patients according to the change on diffusion weighted imaging （DWI）. Results The incidence of various kinds of severe vascular events in 61 patients within 90 days was 16.4% （ 10/61 ）. Among the patients with abnormal change on DWI, the incidence was 50% （8/16）. However the incidence was 4.7% （2/43） in the patients with normal DWI. There was a statistical difference between the two groups （P 〈 0. 001 ）. Whether the patient had diabetes mellitus was related to the prognosis （ OR = 7.6, P 〈 0. 05 ）. Conelusion The prognosis is worse in the TIA patient with diabetes mellitus or positive result on brain DWI. DWI examination appears good prognostic value in patients with TIA.

关 键 词：短暂性脑缺血发作 弥散加权成像 危险因素 预后 

分 类 号：R743[医药卫生—神经病学与精神病学]