临床血痰症状肺癌的组织学类型和部位分析  

Study of the Relationship between the Histological Type,Location and Hemosputum in Patients with Pulmonary Cancer

作　　者：沈维敏[1] 袁明远 龚瑾[1] 李向阳[1] 梁红[1] 严德俊[1] 

机构地区：[1]上海华东医院呼吸科,200040 [2]新加坡康联国际医院癌症与心脏病医学中心,238874

出　　处：《实用癌症杂志》2008年第2期156-158,共3页The Practical Journal of Cancer

摘　　要：目的探讨肺癌患者血痰发生与其部位和组织学类型的关系。方法回顾近5年来经支气管镜检查证实为肺癌患者的病史和放射学资料,分析其血痰症状与组织学类型和生长部位的关系。结果350例肺癌患者有83例有血痰症状(23.71%),其中39例(46.99%)为腺癌,18例(21.69%)为鳞癌,11例(13.25%)为小细胞癌,7例(8.43%)是大细胞癌,5例(6.02%)是肺泡细胞癌,3例(3.62%)是肺转移癌。肺腺癌的血痰症状发生率与其它各类型有显著性差异(P<0.05);83例肺癌中有43例(51.80%)发生在叶支气管或近端支气管,40例(48.20%)发生在叶以下远端支气管。两组肺癌患者血痰症状发生率无显著性差异(P>0.05)。结论出现血痰症状的肺癌组织学类型多为腺癌。肺癌的生长部位与血痰症状的发生无关。Objective The purpose of this study was to determine the trend of tumor location, histological type associated with the occurrence of hemosputum in patients with pulmonary cancer. Methods 350 patients with bronchoendoscopically confirmed pulmonary malignancy were analyzed to study the relationship between the occurrence of hemosputum and the primary tumor location and the histological types. Results 83 out of 350 patients had hemosputum（23.7% ）. Of the 83 patients with hemosputum, 39 （46, 99% ） had adenocarcinoma, 18 （ 21.69% ） had squamous cell carcinoma, 11 （ 13.25 % ） had small cell carcinoma,7 （8.43%） had large cell carcinoma ,5 （6.02%） had alveolar cell carcinoma and 3 （3.62%） had metastatic carcinoma. There was significant difference between patients with adenocarcinoma and patients with other types of lung cancer in clinical hemosputum （P 〈 0.05 ）. No difference was found between peripheral lung cancer and central lung cancer in the occurrence rate of hemosputum （ P 〉 0.05 ）. Conclusion The most frequent histological type of malignancy with hemosputum was adenocarcinoma. The location of lung cancer have no relationship with hemosputum.

关 键 词：肺癌 组织学类型 血痰 部位 

分 类 号：R734.2[医药卫生—肿瘤]