直肠癌放化疗患者心理问题与生活质量评估  

Psychological Problems and QOL in Patients with Rectal Cancer Receiving Chemoradiotherapy

作　　者：丛昌盛[1] 于甬华[1] 刘希军[1] 朱昆莉[1] 

机构地区：[1]山东省肿瘤防治研究院放疗科,250117

出　　处：《实用癌症杂志》2008年第2期166-168,共3页The Practical Journal of Cancer

基　　金：山东省卫生厅2005年科技攻关项目(2005HW138)

摘　　要：目的探讨直肠癌放化疗患者的心理问题与生活质量及相关分析。方法共入组54例患者,入院后完成抑郁自评量表(SDS)、焦虑自评量表(SAS)和SF-36评估。结果局部晚期或术后复发患者较术后常规放化疗患者表现出更高的焦虑和抑郁(P<0.05),表现出更多的消极应对方式(P<0.05),相应生活质量评估中情感角色、生命活力、心理健康及社会功能水平明显偏低(P<0.05)。抑郁、焦虑程度与生活质量评估水平具有明显相关性(P<0.05)。结论局部晚期或术后复发患者只能接受姑息性放化疗,表现出较高水平的焦虑和抑郁,生活质量及免疫学功能均受到较大的影响,常提示预后不良,应该受到临床医护人员的特殊关注。Objective To study the psychological problems and their correlations with QOL（ quality of life） in patients with rectal cancer receiving chemoradiotherapy. Methods 54 patients were enrolled in this study. All patients completed SAS, SDS and SF-36. Results Patients with postoperative relapse or locally advanced cancer experienced a higher level of anxiety and depression （ P 〈 0.05 ）, more negative coping style （ P 〈 0.05 ）, and lower level of role emotion, vitality, mental health and social function（ P 〈 0.05 ） ,compared with the patients receiving conventional postoperative chemoradiotherapy. SAS and SDS significant- ly correlated to quality of life（ P 〈 0.05 ）. Conclusion Patients with postoperative relapse or locally advanced cancer receiving palliative chemoradiotherapy experience a higher level of anxiety and depression, and their quality of life is highly influenced, predicting a poor prognosis. Therefore, their psychological problems are worthy of special attention by clinical staff.

关 键 词：直肠肿瘤 心理学 医学 生活质量 

分 类 号：R735.37[医药卫生—肿瘤]