首次与多次住院精神分裂症病人抗精神病药治疗调查  

Investigation of the antipsychotic drug in treament of the patients of First-time and Multiple Hospitalization drug treatment for rhe first time and that of the repeatedly

作　　者：刘勇[1] 杨琪[1] 杨丽达[1] 

机构地区：[1]合肥市第四人民医院,安徽230022

出　　处：《安徽卫生职业技术学院学报》2008年第1期84-85,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:为了解首次住院与多次住院精神分裂症患者的抗精神病药用药情况。方法:对两个月内出院的233例接受抗精神病药物治疗的精神分裂症患者进行回顾性研究,其中首次住院患者133例,多次住院患者100例,分两组进行比较。结果:首次与多次住院患者精神药物使用频率居首的均为氯氮平,其中多次住院患者高于首次住院者;居前五位的均为氯氮平、舒必利、利培酮、氯丙嗪、奋乃静;非典型抗精神病药物的使用率多次住院组明显高于首次住院组;首次住院组单一用药多于多次住院组,精神药物联合治疗的比例明显少于多次住院组。其差异均有显著性意义。服用前五位抗精神病药物的日平均最大剂量无明显差异。结论:住院精神分裂症病人在抗精神病药联合治疗上及非典型抗精神病药物的使用率上首次住院组少于多次住院组。Objectibe To investigate Investigation of the antipsychotic drug in treament of the patients of Firsttime and Multiple Hospitalization drug treatment for rhe first time and that of the repeatedly. Method 233 inpatients who suffer from schizophrenia （the first-time group 133, the repeated 100 ） were sampled. To compare two groups in some respects retrospectively. Result The rate of using clozapine was the highest among all psychotropic drugs and the repeated group was higher than that of the first group; The first five drugs frepuently used were clozapine, sulpride,resperidone,chlorpromazine and perphanzine; The rate of using atypical psychotropics in the repeated group was significanty higher than that in the first group, the rate of using single drug in the first group is higher than that of repeated group, psychotropic drug combining treatment in the first group was lower than that of repeated group. The difference was significant.The mean maximum daily dose of the first five psychotropics was no significant difference. Conclusion The rate of using psychotropic drug combining treatment and atypical psychotropics in the first group is lower than that of repeated group.

关 键 词：精神分裂症 药物 首次住院 多次住院 

分 类 号：R749.053[医药卫生—神经病学与精神病学]